EIF2S3

Gene Symbol EIF2S3
Entrez Gene 1968
Alt Symbol EIF2, EIF2G, EIF2gamma, eIF-2gA
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
Other Description eIF-2-gamma X|eIF-2gX|eukaryotic translation initiation factor 2 subunit 3|eukaryotic translation initiation factor 2 subunit gamma X|eukaryotic translation initiation factor 2G
Swissprots P41091 B5BTZ4
Accessions CAA07331 EAW99010 EAW99011 EAW99012 P41091 AB451230 BAG70044 AB451353 BAG70167 AF274932 AI133612 AK222577 BAD96297 AK290397 BAF83086 AK312247 BAG35179 BC011945 BC019906 AAH19906 BF435665 CB150474 DQ891794 ABM82720 DQ894977 ABM85903 L19161 AAA19696 NM_001415 NP_001406
Function eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Top Pathways RNA transport

eIF2S3 (K-14) - sc-131149 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

eIF2S3 (N-13) - sc-131150 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-EIF2G antibody - ab33207 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab33207 stained MEF1 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab33207, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-EIF2G antibody - ab33376 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EIF2G antibody (ab33376) at 1/250 dilutionLane 1 : Mouse Embryonic Fibroblast 1Lane 2 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell Lysate (ab7179)Lysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/15000 dilutionPerformed under reducing conditions.

Anti-EIF2G antibody [1H3] - ab129287 from Abcam

Prices $407.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1H3
Detection limit for recombinant proprietary tagged EIF2G is 0.3 ng/ml as a capture antibody.

Anti-EIF2S3 / EIF2G Antibody (aa91-140) - LS-C80805 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.

Anti-EIF2S3 / EIF2G Antibody (aa363-391, AP) - LS-C213725 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S3 / EIF2G Antibody - LS-C155543 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE EIF2S3 / EIF2G antibody diluted at 1:1000

Anti-EIF2S3 / EIF2G Antibody (N-Terminus) - LS-C80806 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-EIF2S3 / EIF2G Antibody (aa363-391, APC) - LS-C213726 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S3 / EIF2G Antibody (aa363-391, FITC) - LS-C213728 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S3 / EIF2G Antibody (aa363-391, Biotin) - LS-C213727 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S3 / EIF2G Antibody (aa363-391, Azide-free, HRP) - LS-C213729 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S3 / EIF2G Antibody (aa363-391, PE) - LS-C213730 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF2S3 / EIF2G Antibody (aa364-391) - LS-C159518 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
EIF2S3 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The EIF2S3 antibody detected the EIF2S3 protein (arrow).

Anti-EIF2S3 / EIF2G Antibody (clone 1H3) IHC-plus™ - LS-B6401 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1H3
Anti-EIF2S3 / EIF2G antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6401 concentration 5 ug/ml.

Anti-EIF2S3 / EIF2G Antibody (aa363-391) - LS-C321062 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

EIF2G Antibody - NBP1-53087 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EIF2G Antibody [NBP1-53087] - Jurkat cell lysate, concentration 5.0ug/ml.

EIF2G Antibody - NBP2-16294 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EIF2G Antibody [NBP2-16294] - Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE gel, diluted at 1:1000.

EIF2G Antibody (2C9) - H00001968-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C9

Monoclonal Anti-EIF2S3, (C-terminal) antibody produced in mouse - SAB1402179 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C9
<B>Immunofluorescence</B><BR/>Monoclonal Anti-EIF2S3: <B>Cat. No. SAB1402179</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Monoclonal Anti-EIF2S3, (C-terminal) antibody produced in mouse - SAB1403759 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H3
<B>Immunoblotting</B><BR/>Monoclonal Anti-EIF2S3: <B>Cat. No. SAB1403759</B>: Antibody concentration: 1 μg/mL. Specific band of ~36 kDa using immunogen protein lysate.

Anti-EIF2S3 antibody produced in rabbit - AV46056 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV46056</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 5.0 μg/mL in cell type Jurkat

Anti-EIF2S3 antibody produced in rabbit - SAB2100661 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-EIF2S3: <B>Cat. No.SAB2100661</B>: EIF2S3 in Transfected 293T cell lysate with EIF2S3 antibody at 1.0 μg/mL.

EIF2S3 Antibody (OALA05619) - OALA05619 from Aviva Systems Biology

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone [clone 1H3]
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