Gene Symbol | ATMIN |
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Entrez Gene | 23300 |
Alt Symbol | ASCIZ, ZNF822 |
Species | Human |
Gene Type | protein-coding |
Description | ATM interactor |
Other Description | ATM INteracting protein|ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein|ATM/ATR-substrate CHEK2-interacting zinc finger protein|ATM/ATR-substrate CHK2-interacting zinc finger protein|zinc finger protein 822 |
Swissprots | O43313 Q68DC9 A8K4H8 |
Accessions | EAW95549 EAW95550 EAW95551 EAW95552 O43313 AB007891 BAA24861 AK025058 AK290943 BAF83632 AK301781 BAH13552 AK302556 BAH13741 BC002701 AAH02701 BI259534 BM693775 BX343387 BX375235 CF593326 CR749457 CAH18291 NM_001300728 NP_001287657 NM_015251 NP_056066 |
Function | Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription. {ECO:0000269|PubMed:15933716, ECO:0000269|PubMed:17525732, ECO:0000269|PubMed:22167198}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15933716, ECO:0000269|PubMed:17525732}. Note=Nuclear, in discrete foci during G1 phase. |
Tissue Specificity | Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle. {ECO:0000269|PubMed:15933716}. |
Human ASCIZ full length protein - ab132268 from Abcam
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Human ASCIZ peptide - ab25305 from Abcam
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ATMIN Antibody Blocking Peptide - LS-E11398 from LifeSpan Bioscience
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ASCIZ Recombinant Protein - H00023300-P01 from Novus Biologicals
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ATMIN / ZNF822 - H00023300-P01-10 from Acris Antibodies
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ATMIN / ZNF822 - H00023300-P01-25 from Acris Antibodies
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ATMIN Peptide - 7777P from ProSci
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ATMIN fusion protein - ag15810 from Proteintech Group
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ATMIN fusion protein - ag7894 from Proteintech Group
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Recombinant Human ATMIN, His-tagged - ATMIN-3694H from Creative Biomart
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Recombinant Human ATM interactor(ATMIN) ,partial - CSB-YP002304HU CSB-EP002304HU CSB-BP002304HU CSB-MP002304HU from Cusabio
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ATM interactor(ATMIN) ,partial, Recombinant Protein - MBS1098577 from MyBioSource
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ASCIZ Recombinant Protein Antigen - NBP2-39079PEP from Novus Biologicals
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ATMIN Peptide, Human - M34GP01115H from Creative Peptides
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ASCIZ Recombinant Protein Antigen - NBP2-58746PEP from Novus Biologicals
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