| Gene Symbol |
ASB8
|
| Entrez Gene |
140461
|
| Alt Symbol |
PP14212
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ankyrin repeat and SOCS box containing 8
|
| Other Description |
ASB-8|ankyrin repeat and SOCS box protein 8|ankyrin repeat and SOCS box-containing 8
|
| Swissprots |
Q547Q2 A8K1P2 Q9H765
|
| Accessions |
EAW57976 Q9H765 AF464877 AAQ04830 AK024908 BAB15033 AK125596 BAC86214 AK289957 BAF82646 AK297013 BAG59546 BC001321 AAH01321 BM837218 BQ009637 CR457336 CAG33617 HQ447366 ADQ31852 XM_005268654 XP_005268711 XM_011537937 XP_011536239 XM_011537938 XP_011536240 NM_024095 NP_077000
|
| Function |
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12559969}.
|
| Tissue Specificity |
Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas. {ECO:0000269|PubMed:12559969}.
|