Gene Symbol | ASB8 |
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Entrez Gene | 140461 |
Alt Symbol | PP14212 |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat and SOCS box containing 8 |
Other Description | ASB-8|ankyrin repeat and SOCS box protein 8|ankyrin repeat and SOCS box-containing 8 |
Swissprots | Q547Q2 A8K1P2 Q9H765 |
Accessions | EAW57976 Q9H765 AF464877 AAQ04830 AK024908 BAB15033 AK125596 BAC86214 AK289957 BAF82646 AK297013 BAG59546 BC001321 AAH01321 BM837218 BQ009637 CR457336 CAG33617 HQ447366 ADQ31852 XM_005268654 XP_005268711 XM_011537937 XP_011536239 XM_011537938 XP_011536240 NM_024095 NP_077000 |
Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12559969}. |
Tissue Specificity | Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas. {ECO:0000269|PubMed:12559969}. |
ASB-8 CRISPR/Cas9 KO Plasmid (h) - sc-408044 from Santa Cruz Biotechnology
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ASB-8 HDR Plasmid (h) - sc-408044-HDR from Santa Cruz Biotechnology
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ASB-8 Double Nickase Plasmid (h) - sc-408044-NIC from Santa Cruz Biotechnology
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ASB-8 Double Nickase Plasmid (h2) - sc-408044-NIC-2 from Santa Cruz Biotechnology
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ASB-8 CRISPR Activation Plasmid (h) - sc-408044-ACT from Santa Cruz Biotechnology
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ASB-8 CRISPR Activation Plasmid (h2) - sc-408044-ACT-2 from Santa Cruz Biotechnology
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ASB-8 Lentiviral Activation Particles (h) - sc-408044-LAC from Santa Cruz Biotechnology
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ASB-8 Lentiviral Activation Particles (h2) - sc-408044-LAC-2 from Santa Cruz Biotechnology
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ASB-8 siRNA (h) - sc-96203 from Santa Cruz Biotechnology
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ASB-8 shRNA Plasmid (h) - sc-96203-SH from Santa Cruz Biotechnology
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ASB-8 shRNA (h) Lentiviral Particles - sc-96203-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU040401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3582 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3582 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09899 from Sigma-Aldrich
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ASB8 siRNA (Human) - CRJ5280 from Cohesion Biosciences
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ASB8 RNAi - H00140461-R01 from Novus Biologicals
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ASB8 - MBS8231708 from MyBioSource
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shRNA set against Human ASB8 (NM_024095.3) - SHH241318 from Creative biogene
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shRNA set against Human ASB8(NM_024095.3) - SHG076823 from Creative biogene
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Human ASB8 siRNA - orb275781 from Biorbyt
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ASB8 shRNA Plasmid (Human) - CHJ5280 from Cohesion Biosciences
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ASB8 miRNA 3'UTR clone - MiUTR1H-00626 from Creative biogene
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