Gene Symbol | ECE2 |
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Entrez Gene | 9718 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | endothelin converting enzyme 2 |
Other Description | endothelin-converting enzyme 2 |
Swissprots | Q96NX3 Q6NTG7 A5PLK8 Q8NFD7 Q6UW36 Q96NX4 Q9BRZ8 O60344 |
Accessions | EAW78273 EAW78274 EAW78275 EAW78276 EAW78277 EAW78278 EAW78279 O60344 AB011176 BAA25530 AF192531 AAG28399 AF428263 AAL30386 AF428264 AAL30387 AF521189 AAM77664 AK293713 BAH11577 AK293891 BAG57280 AK295270 BAG58256 AK296541 BAG59165 AK309236 AY359003 AAQ89362 BC005835 AAH05835 BC012449 AAH12449 BC069005 AAH69005 BC142950 AAI42951 BC146830 AAI46831 BU568980 HQ448359 ADQ32839 NM_001037324 NP_001032401 NM_001100120 NP_001093590 NM_001100121 NP_001093591 NM_014693 NP_055508 NM_032331 NP_115707 |
Function | Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta- amyloid peptide accumulation in brain. May also have methyltransferase activity. {ECO:0000269|PubMed:12560336}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasmic granule membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level). {ECO:0000269|PubMed:17188679}. |
ECE2 protein (His-DHFR tag) - ab127457 from Abcam
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Human ECE2 full length protein - ab132791 from Abcam
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ECE2 Antibody Blocking Peptide - LS-E16470 from LifeSpan Bioscience
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Recombinant Human ECE-2 Protein - H00009718-P01 from Novus Biologicals
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Recombinant Human ECE-2, CF - 1645-ZN-010 from R&D Systems
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ECE2 peptide - orb72632 from Biorbyt
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Ece2 Blocking Peptide - 33R-10191 from Fitzgerald
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ECE2 - H00009718-P01-10 from Acris Antibodies
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ECE2 - H00009718-P01-25 from Acris Antibodies
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ECE2 fusion protein - Ag7963 from Proteintech Group
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ECE2 fusion protein - Ag7706 from Proteintech Group
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Recombinant Human ECE2, Fc tagged - ECE2-690H from Creative Biomart
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Recombinant Human ECE2, His tagged - ECE2-3813H from Creative Biomart
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Recombinant Human ECE2, His-tagged - ECE2-12265H from Creative Biomart
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Recombinant Human ECE2, His&Val-tagged - ECE2-529H from Creative Biomart
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ECE-2 - PN201513 from Elabscience
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Recombinant Endothelin Converting Enzyme 2 (ECE2) - RPF414Hu01 from Uscn Life Science Inc.
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Human ECE-2 Protein (Fc Tag) - 10207-H01H-10 from Sino Biological
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Human ECE-2 Protein (His Tag) - 10207-H07H-10 from Sino Biological
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Recombinant Endothelin Converting Enzyme 2 (ECE2) - RPF414Hu01 from Cloud-clone
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Recombinant Human Endothelin-converting enzyme 2(ECE2) ,partial - CSB-YP007372HU CSB-EP007372HU CSB-BP007372HU CSB-MP007372HU from Cusabio
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Recombinant Human ECE-2 Protein, CF - 1645-ZN from R&D Systems
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ECE2 Protein - abx163820 from Abbexa
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Recombinant Human ECE-2 Protein (His tag) - PKSH031761 from Elabscience
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Recombinant Human ECE-2 Protein (Fc tag) - PKSH031762 from Elabscience
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