ABCA7

Gene Symbol	ABCA7
Entrez Gene	10347
Alt Symbol	ABCA-SSN, ABCX
Species	Human
Gene Type	protein-coding
Description	ATP-binding cassette, sub-family A (ABC1), member 7
Other Description	ATP-binding cassette sub-family A member 7|autoantigen SS-N|macrophage ABC transporter
Swissprots	Q9BZC4 Q8IZY2 Q96S58 Q9UKP8 Q9NR73
Accessions	AAN04657 CCQ43618 EAW69556 EAW69557 EAW69558 EAW69559 EAW69560 EAW69561 EAW69562 EAW69563 EAW69564 Q8IZY2 AB055390 BAB62294 AF140342 AAF06727 AF250238 AAF85794 AF328787 AAK00959 AK097344 BAG53455 AK301108 BAG62707 AK310127 AK310909 AL137481 CAB70762 BC172426 AAI72426 BU675136 CD629701 DC405492 XM_006722616 XP_006722679 XM_006722617 XP_006722680 XM_006722618 XP_006722681 XM_011527628 XP_011525930 XM_011527629 XP_011525931 XM_011527630 XP_011525932 XM_011527631 XP_011525933 XM_011527632 XP_011525934 XM_011527633 XP_011525935 XM_011527634 XP_011525936 XM_011527635 XP_011525937 XM_011527636 XP_011525938 XR_936148 XR_936149 XR_936150 XR_936151 XR_936152 XR_936153 XR_936154 XR_936155 NM_019112 NP_061985 NM_033308
Function	Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation. {ECO:0000269|PubMed:12917409, ECO:0000269|PubMed:12925201, ECO:0000269|PubMed:14570867, ECO:0000269|PubMed:14592415}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney. Isoform 2 may localize to the endoplasmic reticulum.
Tissue Specificity	Expressed in leukocytes (at protein level). Widely expressed. Highly expressed in myelo-lymphatic tissues including peripheral leukocytes, thymus, spleen and bone marrow. Isoform 2 is more abundant in lymph node, spleen, thymus and trachea than isoform 1 which is more strongly expressed in brain and bone marrow. {ECO:0000269|PubMed:10873640, ECO:0000269|PubMed:11435699, ECO:0000269|PubMed:14592415}.
Top Pathways	ABC transporters

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

ATP-binding cassette sub-family A member 7 (ABCA7), Human, ELISA Kit - E01A1133 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 250-5000pg/ml

ATP-binding cassette sub-family A member 7, ABCA7, Human, ELISA Kit - E15004h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.156-10.00 ng/ml

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7234086 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7213650 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7211637 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7242114 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7244185 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7249062 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7217584 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7232438 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7227879 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7229686 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-binding cassette sub-family A member 7 (ABCA7), ELISA Kit - MBS7217406 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP binding cassette sub family A member 7 (ABCA7), ELISA Kit - MBS7249135 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Rat ABCA7 ELISA Kit (Custom ELISA) - LS-F17614 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse ABCA7 ELISA Kit (Custom ELISA) - LS-F17613 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human ATP-binding cassette sub-family A member 7 ELISA Kit - abx251008 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human ATP-binding cassette sub-family A member 7 ELISA Kit - EKE55362 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.045 ng/ml Range 0.156-10 ng/ml

ABCA7 - EKH3416 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

ABCA7 ELISA Kit (Human) (OKEH02427) - OKEH02427 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 0.045 ng/mL Range 0.156 - 10 ng/mL

Human ABCA7 ELISA Kit - E003961 from Biobool Category ELISA Kit Sensitivity 1.0 pg/mL.

Human ATP-binding cassette sub-family A member 7 ELISA Kit - EK3554 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Sensitivity less than 0.045ng/ml Range 0.156-10 ng/ml

ATP-binding cassette sub-family A member 7, ELISA Kit - MBS2881027 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.156-10 ng/ml

ATP-binding cassette sub-family A member 7, ELISA Kit - MBS9427388 from MyBioSource Category ELISA Kit Prices $670.00 Sizes 96 tests Sensitivity Less than 0.045ng/mL Range 0.156-10 ng/mL

ATP-binding cassette sub-family A member 7, ELISA Kit - MBS764146 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

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