ABCC1

Gene Symbol ABCC1
Entrez Gene 4363
Alt Symbol ABC29, ABCC, GS-X, MRP, MRP1
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Other Description ATP-binding cassette transporter variant ABCC1delta-ex13|ATP-binding cassette transporter variant ABCC1delta-ex13&14|ATP-binding cassette transporter variant ABCC1delta-ex25|ATP-binding cassette transporter variant ABCC1delta-ex25&26|LTC4 transporter|leukotriene C(4) transporter|multidrug resistance-associated protein 1
Swissprots Q9UQ97 P78419 O43333 P33527 Q9UQ99 Q59GI9 C9JPJ4 O14819 A3RJX2 Q9UQA0
Accessions AAB82786 AAB83979 AAB83980 AAB83981 AAB83982 AAB83983 AAC05808 AAC15784 ABN79590 EAW53936 EAW53937 EAW53938 EAW53939 EAW53940 EAW53941 EAW53942 EAW53943 EAW53944 EAW53945 EAW53946 EAW53947 EAW53948 EAW53949 P33527 AB209120 BAD92357 AJ003198 AK311015 BC001636 AAH01636 BC156353 AAI56354 BC157105 AAI57106 BX648866 CR749835 CAH18691 HQ917064 AEK86268 HQ917065 AEK86269 HQ917066 AEK86270 HQ917067 AEK86271 L05628 AAB46616 X78338 XM_011522497 XP_011520799 XM_011522498 XP_011520800 NM_004996 NP_004987 NM_019862 NM_019898 NM_019899 NM_019900 NM_019901 NM_019902
Function Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. {ECO:0000269|PubMed:10064732, ECO:0000269|PubMed:11114332, ECO:0000269|PubMed:16230346}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16230346}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:16230346}.
Tissue Specificity Lung, testis and peripheral blood mononuclear cells.
Top Pathways ABC transporters, Vitamin digestion and absorption, MicroRNAs in cancer, Sphingolipid signaling pathway

Human MRP1 protein fragment - ab152539 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab152539 stained with Coomassie Blue.

ABCC1-Antibody-C-term-Blocking-Peptide - BP6596b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MRP1 blocking peptide - GTX88617-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Rat, Bovine

ABCC1 Blocking Peptide - 33R-4941 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

MRMP1 Peptide - AC21-1625-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

ABCC1 / MRP1 - H00004363-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

ABCC1 / MRP1 - H00004363-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

ABCC1 Peptide - 46-794P from ProSci

Category Peptide
Species Human

Recombinant Human ABCC1 - ABCC1-285H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Multidrug Resistance Associated Protein 1 (MRP1) - RPB068Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Multidrug Resistance Associated Protein 1 (MRP1) - RPB068Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Multidrug Resistance Associated Protein 1 (MRP1) - RPB068Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

Recombinant Multidrug Resistance Associated Protein 1 (MRP1) - RPB068Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

MRP1 Partial Recombinant Protein - H00004363-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

ABCC1, Peptide - MBS426249 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Bovine

ABCC1 Peptide, Human - M34GP00049H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Multidrug resistance-associated protein 1 (ABCC1), partial, Recombinant Protein - MBS1160885 from MyBioSource

Category Protein
Prices $1,075.00, $1,075.00, $1,305.00, $1,305.00, $1,630.00, $1,630.00, $2,090.00, $2,090.00, $2,125.00, $3,215.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Human ABCC1 protein - orb419225 from Biorbyt

Category Protein
Species Human

ABCC1 Immunizing peptide - orb54971 from Biorbyt

Category Peptide

Recombinant Human ABCC1 Protein (1248-1531 aa), His-tagged - ABCC1-2325H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human ABCC1 Protein, GST-Tagged - ABCC1-042H from Creative Biomart

Category Protein
Source Wheat Germ
Species Human
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