ABCC1

Gene Symbol ABCC1
Entrez Gene 4363
Alt Symbol ABC29, ABCC, GS-X, MRP, MRP1
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Other Description ATP-binding cassette transporter variant ABCC1delta-ex13|ATP-binding cassette transporter variant ABCC1delta-ex13&14|ATP-binding cassette transporter variant ABCC1delta-ex25|ATP-binding cassette transporter variant ABCC1delta-ex25&26|LTC4 transporter|leukotriene C(4) transporter|multidrug resistance-associated protein 1
Swissprots Q9UQ97 P78419 O43333 P33527 Q9UQ99 Q59GI9 C9JPJ4 O14819 A3RJX2 Q9UQA0
Accessions AAB82786 AAB83979 AAB83980 AAB83981 AAB83982 AAB83983 AAC05808 AAC15784 ABN79590 EAW53936 EAW53937 EAW53938 EAW53939 EAW53940 EAW53941 EAW53942 EAW53943 EAW53944 EAW53945 EAW53946 EAW53947 EAW53948 EAW53949 P33527 AB209120 BAD92357 AJ003198 AK311015 BC001636 AAH01636 BC156353 AAI56354 BC157105 AAI57106 BX648866 CR749835 CAH18691 HQ917064 AEK86268 HQ917065 AEK86269 HQ917066 AEK86270 HQ917067 AEK86271 L05628 AAB46616 X78338 XM_011522497 XP_011520799 XM_011522498 XP_011520800 NM_004996 NP_004987 NM_019862 NM_019898 NM_019899 NM_019900 NM_019901 NM_019902
Function Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. {ECO:0000269|PubMed:10064732, ECO:0000269|PubMed:11114332, ECO:0000269|PubMed:16230346}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16230346}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:16230346}.
Tissue Specificity Lung, testis and peripheral blood mononuclear cells.
Top Pathways ABC transporters, Vitamin digestion and absorption, MicroRNAs in cancer, Sphingolipid signaling pathway

MRP1 CRISPR/Cas9 KO Plasmid (h) - sc-400456 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 HDR Plasmid (h) - sc-400456-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 Double Nickase Plasmid (h) - sc-400456-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 Double Nickase Plasmid (h2) - sc-400456-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 CRISPR Activation Plasmid (h) - sc-400456-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 CRISPR Activation Plasmid (h2) - sc-400456-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 Lentiviral Activation Particles (h) - sc-400456-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 Lentiviral Activation Particles (h2) - sc-400456-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP1 siRNA (h) - sc-35962 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRP1 shRNA Plasmid (h) - sc-35962-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRP1 shRNA (h) Lentiviral Particles - sc-35962-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU076261 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0013 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0014 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0015 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

ABCC1 siRNA (Human) - CRH2965 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCC1 - MBS8222077 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ABCC1 (NM_004996.3) - SHH229070 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ABCC1(NM_004996.3) - SHG023707 from Creative biogene

Category siRNA
Species Reactivities Human

Human ABCC1 siRNA - orb263467 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCC1 shRNA Plasmid (Human) - CHH2965 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ABCC1 miRNA 3'UTR clone - MiUTR1H-00035 from Creative biogene

Species Reactivities Human
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