Gene Symbol | SIAH3 |
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Entrez Gene | 283514 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | siah E3 ubiquitin protein ligase family member 3 |
Other Description | seven in absentia homolog 3|siah-3 |
Swissprots | Q8N8M6 B7ZBP0 Q8IW03 |
Accessions | Q8IW03 AK125411 BC041372 AAH41372 BC148396 AAI48397 DA804734 NM_198849 NP_942146 |
Function | Negative regulator of PARK2 translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PARK2 targeting to dysfunctional depolarized mitochondria. {ECO:0000269|PubMed:24270810}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:24270810}. |
seven in absentia homolog 3 (Drosophila) , ELISA Kit - MBS9339702 from MyBioSource
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Human SIAH3 ELISA Kit - E035005 from Biobool
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