| Gene Symbol |
SIAH3
|
| Entrez Gene |
283514
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
siah E3 ubiquitin protein ligase family member 3
|
| Other Description |
seven in absentia homolog 3|siah-3
|
| Swissprots |
Q8N8M6 B7ZBP0 Q8IW03
|
| Accessions |
Q8IW03 AK125411 BC041372 AAH41372 BC148396 AAI48397 DA804734 NM_198849 NP_942146
|
| Function |
Negative regulator of PARK2 translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PARK2 targeting to dysfunctional depolarized mitochondria. {ECO:0000269|PubMed:24270810}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:24270810}.
|