AMOTL1

Gene Symbol AMOTL1
Entrez Gene 154810
Alt Symbol JEAP
Species Human
Gene Type protein-coding
Description angiomotin like 1
Other Description angiomotin-like protein 1|junction-enriched and associated protein
Swissprots Q8IY63 Q63HK7 Q8WXD1 Q8TEN8 Q8NDN0 Q96CM5
Accessions EAW66943 EAW66944 EAW66945 Q8IY63 AF453742 AAL49764 AK024350 AK074084 BAB84910 AK093699 BAC04218 AL137281 AL833833 CAD38693 AM393663 CAL38539 BC014126 AAH14126 BC018449 BC037539 AAH37539 BC040683 BX648729 CAH56180 XM_005273798 XP_005273855 XM_005273801 XP_005273858 XM_006718772 XP_006718835 XM_011542626 XP_011540928 XM_011542627 XP_011540929 XM_011542628 XP_011540930 NM_001301007 NP_001287936 NM_130847 NP_570899
Function Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. {ECO:0000269|PubMed:22362771}.
Subcellular Location Cell junction, tight junction {ECO:0000250}.
Top Pathways Tight junction

Human AMOTL1 ORF Clone(NM_130847.2) - CDCR315870 from Creative biogene

Species Human
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