| Gene Symbol |
AMOTL1
|
| Entrez Gene |
154810
|
| Alt Symbol |
JEAP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
angiomotin like 1
|
| Other Description |
angiomotin-like protein 1|junction-enriched and associated protein
|
| Swissprots |
Q8IY63 Q63HK7 Q8WXD1 Q8TEN8 Q8NDN0 Q96CM5
|
| Accessions |
EAW66943 EAW66944 EAW66945 Q8IY63 AF453742 AAL49764 AK024350 AK074084 BAB84910 AK093699 BAC04218 AL137281 AL833833 CAD38693 AM393663 CAL38539 BC014126 AAH14126 BC018449 BC037539 AAH37539 BC040683 BX648729 CAH56180 XM_005273798 XP_005273855 XM_005273801 XP_005273858 XM_006718772 XP_006718835 XM_011542626 XP_011540928 XM_011542627 XP_011540929 XM_011542628 XP_011540930 NM_001301007 NP_001287936 NM_130847 NP_570899
|
| Function |
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. {ECO:0000269|PubMed:22362771}.
|
| Subcellular Location |
Cell junction, tight junction {ECO:0000250}.
|
| Top Pathways |
Tight junction
|