Gene Symbol | FDX1 |
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Entrez Gene | 2230 |
Alt Symbol | ADX, FDX, LOH11CR1D |
Species | Human |
Gene Type | protein-coding |
Description | ferredoxin 1 |
Other Description | adrenal ferredoxin|adrenodoxin, mitochondrial|ferredoxin-1|hepatoredoxin|mitochondrial adrenodoxin |
Swissprots | P10109 Q53YD6 B0YJ14 |
Accessions | AAA35855 AAA35856 AAA50462 AAD15277 ACA05992 EAW67132 P10109 AA505582 AB096243 BC010284 AAH10284 BC017063 AAH17063 BQ650029 BT006681 AAP35327 CN333249 DB459133 J03548 AAA96806 M18003 AAA76853 M34788 AAA35829 NM_004109 NP_004100 |
Function | Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. {ECO:0000269|PubMed:20547883, ECO:0000269|PubMed:21636783}. |
Subcellular Location | Mitochondrion matrix {ECO:0000269|PubMed:20547883}. |
Tissue Specificity | Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level). {ECO:0000269|PubMed:20547883}. |
ADX (H-71) - sc-368663 from Santa Cruz Biotechnology
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ADX (T-15) - sc-30282 from Santa Cruz Biotechnology
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Anti-Adrenodoxin antibody [EPR4629] - ab108257 from Abcam
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Anti-Adrenodoxin antibody [EPR4630] - ab109312 from Abcam
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Anti-FDX1 / ADX Antibody (Internal, clone EPR4630) - LS-C138268 from LifeSpan Bioscience
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Anti-FDX1 / ADX Antibody (Internal, clone EPR4629) - LS-C138367 from LifeSpan Bioscience
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Anti-FDX1 / ADX Antibody (clone 1E7) - LS-C197209 from LifeSpan Bioscience
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FDX1 Antibody - NBP1-89227 from Novus Biologicals
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FDX1 Antibody - NBP2-38946 from Novus Biologicals
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FDX1 Antibody (1G9) - H00002230-M03 from Novus Biologicals
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Anti-FDX1 antibody produced in rabbit - HPA041630 from Sigma-Aldrich
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Monoclonal Anti-FDX1, (C-terminal) antibody produced in mouse - SAB1403811 from Sigma-Aldrich
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Monoclonal Anti-FDX1 antibody produced in mouse - SAB1401137 from Sigma-Aldrich
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Monoclonal Anti-FDX1 antibody produced in mouse - SAB1401136 from Sigma-Aldrich
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Anti-FDX1 (71-85) antibody produced in rabbit - F9806 from Sigma-Aldrich
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Anti -FDX1 (Adrenodoxin, Mitochondrial, Adrenal Ferredoxin, Ferredoxin-1, Hepatoredoxin,ADX) - 126739 from USBiological Life Science
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Anti -FDX1 (Adrenodoxin, Mitochondrial, Adrenal Ferredoxin, Ferredoxin-1, Hepatoredoxin,ADX) (AP) - 126739-AP from USBiological Life Science
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Anti -FDX1 (Adrenodoxin, Mitochondrial, Adrenal Ferredoxin, Ferredoxin-1, Hepatoredoxin,ADX) (Biotin) - 126739-Biotin from USBiological Life Science
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Anti -FDX1 (Adrenodoxin, Mitochondrial, Adrenal Ferredoxin, Ferredoxin-1, Hepatoredoxin,ADX) (FITC) - 126739-FITC from USBiological Life Science
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Anti -FDX1 (Adrenodoxin, Mitochondrial, Adrenal Ferredoxin, Ferredoxin-1, Hepatoredoxin,ADX) (HRP) - 126739-HRP from USBiological Life Science
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Anti -FDX1 (Adrenodoxin, Mitochondrial, Adrenal Ferredoxin, Ferredoxin-1, Hepatoredoxin,ADX) (PE) - 126739-PE from USBiological Life Science
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Ferredoxin-1 (FDX1) antibody - 12592-1-AP from Acris Antibodies
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Ferredoxin-1 (FDX1) antibody - H00002230-M01 from Acris Antibodies
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Ferredoxin-1 (FDX1) antibody - H00002230-M02 from Acris Antibodies
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Ferredoxin-1 (FDX1) antibody - H00002230-M03 from Acris Antibodies
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