ITGA2

Gene Symbol	ITGA2
Entrez Gene	3673
Alt Symbol	BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2
Species	Human
Gene Type	protein-coding
Description	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Other Description	CD49 antigen-like family member B|VLA2 receptor, alpha-2 subunit|collagen receptor|human platelet alloantigen system 5|integrin alpha-2|platelet antigen Br|platelet glycoprotein GPIa|platelet membrane glycoprotein Ia|very late activation protein 2 receptor, alpha-2 subunit
Swissprots	Q14595 P17301
Accessions	AAA16619 AAC94975 AAD14096 AAF77577 AAM34795 ADZ28531 ADZ28532 ADZ28533 AEO14637 AEO14638 CCF76999 EAW54872 EAW54873 P17301 AK307952 AU126174 BC143505 BC143508 BC143509 BC143511 BC143512 BC148596 AAI48597 BC156715 AAI56716 BE048389 BF355124 BG288116 BG494837 BG771368 BM828183 BM979113 BP280760 BP381403 CA442768 CK904145 CN272390 DA343078 DA545055 X17033 CAA34894 NM_002203 NP_002194 NR_073103 NR_073104 NR_073105 NR_073106 NR_073107
Function	Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Proteoglycans in cancer, Phagosome, PI3K-Akt signaling pathway, Focal adhesion, Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Integrin alpha 2 protein fragment - ab158772 from Abcam Category Protein Source Wheat germ Species Human

ITGA2 / CD49b Antibody Blocking Peptide - LS-E5399 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ITGA2 / CD49b Antibody Blocking Peptide - LS-E23441 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ITGA2 / CD49b Antibody Blocking Peptide - LS-E9916 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ITGA2 / CD49b Antibody Blocking Peptide - LS-E29645 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ITGA2 / CD49b Antibody Blocking Peptide - LS-E29646 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Integrin alpha 2/CD49b Protein - H00003673-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ITGA2-Antibody-C-term-Blocking-Peptide - BP17907b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ITGA2-Antibody-C-term-Blocking-Peptide - BP9051b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Integrin alpha 2 beta 1, CF - 5698-A2-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived

Recombinant Mouse Integrin alpha 2 beta 1, CF - 7828-A2-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived

CD49b / ITGA2 - H00003673-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD49b / ITGA2 - H00003673-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Integrin Alpha 2 (ITGa2), Human - 20-7566 from ARP American Research Products Category Protein Prices $369.00 Sizes 50 µg Source E.coli Species Human

Integrin Alpha 2 (ITGa2), Human - 20-7567 from ARP American Research Products Category Protein Prices $369.00 Sizes 50 µg Source E.coli Species Human

Recombinant Human C1QBP, Met&His-tagged - C1QBP-712H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human ITGA2&ITGB1 - ITGA2&ITGB1-738H from Creative Biomart Category Protein Source CHO cells Species Human

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Hu03 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Hu02 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Integrin Alpha 2 (ITGa2) - RPB228Hu03 from Cloud-clone Category Protein Source E.coli Species Human

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