ITGA2

Gene Symbol ITGA2
Entrez Gene 3673
Alt Symbol BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2
Species Human
Gene Type protein-coding
Description integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
Other Description CD49 antigen-like family member B|VLA2 receptor, alpha-2 subunit|collagen receptor|human platelet alloantigen system 5|integrin alpha-2|platelet antigen Br|platelet glycoprotein GPIa|platelet membrane glycoprotein Ia|very late activation protein 2 receptor, alpha-2 subunit
Swissprots Q14595 P17301
Accessions AAA16619 AAC94975 AAD14096 AAF77577 AAM34795 ADZ28531 ADZ28532 ADZ28533 AEO14637 AEO14638 CCF76999 EAW54872 EAW54873 P17301 AK307952 AU126174 BC143505 BC143508 BC143509 BC143511 BC143512 BC148596 AAI48597 BC156715 AAI56716 BE048389 BF355124 BG288116 BG494837 BG771368 BM828183 BM979113 BP280760 BP381403 CA442768 CK904145 CN272390 DA343078 DA545055 X17033 CAA34894 NM_002203 NP_002194 NR_073103 NR_073104 NR_073105 NR_073106 NR_073107
Function Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Proteoglycans in cancer, Phagosome, PI3K-Akt signaling pathway, Focal adhesion, Dilated cardiomyopathy

Integrin α2 CRISPR/Cas9 KO Plasmid (h) - sc-400913 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 HDR Plasmid (h) - sc-400913-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 Double Nickase Plasmid (h) - sc-400913-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 Double Nickase Plasmid (h2) - sc-400913-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 CRISPR Activation Plasmid (h) - sc-400913-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 CRISPR Activation Plasmid (h2) - sc-400913-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 Lentiviral Activation Particles (h) - sc-400913-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 Lentiviral Activation Particles (h2) - sc-400913-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin α2 siRNA (h) - sc-29371 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin α2 shRNA Plasmid (h) - sc-29371-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin α2 shRNA (h) Lentiviral Particles - sc-29371-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU040531 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1533 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1533 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ITGA2 siRNA (Human) - CRH2464 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Integrin alpha 2/CD49b RNAi - H00003673-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ITGA2 - MBS829377 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ITGA2 (NM_002203.3) - SHH321161 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ITGA2(NM_002203.3) - SHL180782 from Creative biogene

Category siRNA
Species Reactivities Human

Human ITGA2 siRNA - orb262966 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ITGA2 shRNA Plasmid (Human) - CHH2464 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ITGA2 miRNA 3'UTR clone - MiUTR1H-05019 from Creative biogene

Species Reactivities Human
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