TRMU

Gene Symbol TRMU
Entrez Gene 55687
Alt Symbol MTO2, MTU1, TRMT, TRMT1, TRNT1
Species Human
Gene Type protein-coding
Description tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Other Description MTO2 homolog|mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase|mitochondrial tRNA-specific 2-thiouridylase 1
Swissprots Q9NWC1 Q6ICC3 Q66K31 A8K3U7 Q05C99 Q5W9C8 O75648
Accessions AAL35970 EAW73422 EAW73423 EAW73424 EAW73425 EAW73426 O75648 AB178028 BAD66875 AK000212 AK001002 BAA91462 AK055295 AK093743 AK290712 BAF83401 AK295173 BAG58183 AK303020 BAG64147 AY062123 AAL38183 BC012076 BC027991 AAH27991 BC066593 BC080631 AAH80631 BM755897 BX952612 CN365141 CR456445 CAG30331 CU013043 CAK54474 CU013331 CAK54773 DN997542 DQ309998 ABC46690 DQ309999 ABC46691 DQ310000 ABC46692 XM_005261678 XP_005261735 XM_005261681 XP_005261738 XM_011530271 XP_011528573 XM_011530272 XP_011528574 XM_011530273 XP_011528575 XM_011530274 XP_011528576 XM_011530275 XP_011528577 NM_001282782 NP_001269711 NM_001282783 NP_001269712 NM_001282784 NP_001269713 NM_001282785 NP_001269714 NM_018006 NP_060476 NR_104240 NR_104241 NM_001008569 NM_001008571
Function Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2- thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base. {ECO:0000269|PubMed:15509579, ECO:0000269|PubMed:15944150, ECO:0000269|PubMed:16826519}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:15509579, ECO:0000269|PubMed:15944150, ECO:0000269|PubMed:16513084, ECO:0000269|PubMed:16826519}.
Tissue Specificity Ubiquitous. Abundantly expressed in tissues with high metabolic rates including heart, liver, kidney, and brain. {ECO:0000269|PubMed:16513084}.
Top Pathways Sulfur relay system

TRMU CRISPR/Cas9 KO Plasmid (h) - sc-407811 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU HDR Plasmid (h) - sc-407811-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU Double Nickase Plasmid (h) - sc-407811-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU Double Nickase Plasmid (h2) - sc-407811-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU CRISPR Activation Plasmid (h) - sc-407811-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU CRISPR Activation Plasmid (h2) - sc-407811-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU Lentiviral Activation Particles (h) - sc-407811-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU Lentiviral Activation Particles (h2) - sc-407811-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRMU siRNA (h) - sc-76757 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRMU shRNA Plasmid (h) - sc-76757-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRMU shRNA (h) Lentiviral Particles - sc-76757-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRNT1 RNAi - H00051095-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU120351 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22044 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22044 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02804 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02804

TRMU siRNA (Human) - CRJ0833 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRMU - MBS8217024 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRMU (NM_018006.4) - SHH435376 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TRMU(NM_018006.4) - SHL096112 from Creative biogene

Category siRNA
Species Reactivities Human

TRMU shRNA Plasmid (Human) - CHJ0833 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRMU miRNA 3'UTR clone - MiUTR1H-10775 from Creative biogene

Species Reactivities Human
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