Gene Symbol | KRT2 |
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Entrez Gene | 3849 |
Alt Symbol | CK-2e, K2e, KRT2A, KRT2E, KRTE |
Species | Human |
Gene Type | protein-coding |
Description | keratin 2, type II |
Other Description | cytokeratin-2e|epithelial keratin-2e|keratin, type II cytoskeletal 2 epidermal|keratin-2 epidermis|keratin-2e|type-II keratin Kb2 |
Swissprots | Q4VAQ2 P35908 |
Accessions | AAB81946 EAW96641 P35908 AL598277 BC096294 AAH96294 BC099643 AAH99643 BC099644 AAH99644 M99061 AAC83410 NM_000423 NP_000414 |
Function | Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. {ECO:0000269|PubMed:12598329, ECO:0000269|PubMed:1380918}. |
Tissue Specificity | Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization. {ECO:0000269|PubMed:10233306, ECO:0000269|PubMed:12598329, ECO:0000269|PubMed:1380918}. |
Cytokeratin 2E (Ks2.342.7.1) - sc-58731 from Santa Cruz Biotechnology
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Keratin 2 (U-25) - sc-101993 from Santa Cruz Biotechnology
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Anti-Cytokeratin 2e antibody - ab197365 from Abcam
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Anti-Cytokeratin 2e antibody - ab96145 from Abcam
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Anti-Cytokeratin 2e antibody - ab135115 from Abcam
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Anti-Cytokeratin 2e antibody [EPR10911] - ab170106 from Abcam
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (N-Terminus) - LS-C22706 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (N-Terminus) - LS-C22708 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa2-23) - LS-C22705 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (N-Terminus, clone Ks 2.342.7.1) - LS-C84883 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (clone KS 2.342.7.1) - LS-C121867 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (clone Ks2.398.3.1) - LS-C193404 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (clone Ks2,342,7,1) - LS-C149073 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa2-23) - LS-C193750 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (clone Ks 2.342.7.1) - LS-C202210 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa508-685) - LS-C294998 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa508-685, Biotin) - LS-C297091 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa368-507, Biotin) - LS-C297178 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa7-160, Biotin) - LS-C297785 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa7-160, FITC) - LS-C301744 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa508-685, FITC) - LS-C303318 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa368-507, FITC) - LS-C304032 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa351-400) - LS-C40345 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa368-507) - LS-C295003 from LifeSpan Bioscience
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Anti-KRT2 / CK2 / Cytokeratin 2 Antibody (aa7-160) - LS-C294997 from LifeSpan Bioscience
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