DAZ1

Gene Symbol DAZ1
Entrez Gene 1617
Alt Symbol DAZ, SPGY
Species Human
Gene Type protein-coding
Description deleted in azoospermia 1
Other Description deleted in azoospermia protein 1
Swissprots Q9NQZ4 Q1RMF9 Q9NQZ3
Accessions AAL24501 AAR31726 AAR31727 AAR31728 AAR31729 AAS55959 AAS78586 Q9NQZ3 AF271087 AAF91405 AF271088 AAF91406 AK310133 BC114927 AAI14928 DB461291 U66077 XM_011531482 XP_011529784 XM_011531483 XP_011529785 NM_004081 NP_004072
Function RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. {ECO:0000269|PubMed:19865085}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11058556}. Nucleus {ECO:0000269|PubMed:11058556}. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
Tissue Specificity Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level). {ECO:0000269|PubMed:10936047, ECO:0000269|PubMed:18385127, ECO:0000269|PubMed:19223287}.

DAZ1 CRISPR/Cas9 KO Plasmid (h) - sc-416236 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ1 HDR Plasmid (h) - sc-416236-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ1 Double Nickase Plasmid (h) - sc-416236-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ1 Double Nickase Plasmid (h2) - sc-416236-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ1 CRISPR Activation Plasmid (h) - sc-416236-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ1 CRISPR Activation Plasmid (h2) - sc-416236-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ1 Lentiviral Activation Particles (h) - sc-416236-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ1 Lentiviral Activation Particles (h2) - sc-416236-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DAZ siRNA (h) - sc-270452 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAZ shRNA Plasmid (h) - sc-270452-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAZ shRNA (h) Lentiviral Particles - sc-270452-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAZ1 RNAi - H00001617-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU128261 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6936 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6936 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DAZ1 siRNA (Human) - CRH1139 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAZ1 - MBS8200078 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAZ1 shRNA Plasmid (Human) - CHH1139 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DAZ1 miRNA 3'UTR clone - MiUTR3H-03042 from Creative biogene

Species Reactivities Human
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