Gene Symbol | DAZ1 |
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Entrez Gene | 1617 |
Alt Symbol | DAZ, SPGY |
Species | Human |
Gene Type | protein-coding |
Description | deleted in azoospermia 1 |
Other Description | deleted in azoospermia protein 1 |
Swissprots | Q9NQZ4 Q1RMF9 Q9NQZ3 |
Accessions | AAL24501 AAR31726 AAR31727 AAR31728 AAR31729 AAS55959 AAS78586 Q9NQZ3 AF271087 AAF91405 AF271088 AAF91406 AK310133 BC114927 AAI14928 DB461291 U66077 XM_011531482 XP_011529784 XM_011531483 XP_011529785 NM_004081 NP_004072 |
Function | RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells. {ECO:0000269|PubMed:19865085}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11058556}. Nucleus {ECO:0000269|PubMed:11058556}. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis. |
Tissue Specificity | Testis-specific. Expression restricted to premeiotic germ cells, particularly in spermatogonia (at protein level). {ECO:0000269|PubMed:10936047, ECO:0000269|PubMed:18385127, ECO:0000269|PubMed:19223287}. |
DAZ1 Antibody - 12706 from Cell Signaling Technology
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DAZ (Z6Q) - sc-100705 from Santa Cruz Biotechnology
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DAZ (N-16) - sc-27334 from Santa Cruz Biotechnology
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Anti-DAZ antibody [EPR10837] - ab174306 from Abcam
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Anti-DAZ1 antibody - ab54605 from Abcam
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Anti-DAZ1 antibody - ab54607 from Abcam
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Anti-DAZ1 antibody - ab80147 from Abcam
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Anti-DAZ1 antibody [3G10] - ab115548 from Abcam
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Anti-DAZ1 antibody - C-terminal - ab201153 from Abcam
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Anti-DAZ1 / DAZ Antibody (clone 3G10) IHC-plus⢠- LS-B4311 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus, AP) - LS-C276710 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus, APC) - LS-C276711 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus, Biotin) - LS-C276712 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus, FITC) - LS-C276713 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus, Azide-free, HRP) - LS-C276714 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus) - LS-C112232 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus, PE) - LS-C276715 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (N-Terminus) - LS-C330406 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody - LS-C341766 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (clone 3E3) - LS-C133147 from LifeSpan Bioscience
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Anti-DAZ1 / DAZ Antibody (clone 3A4) - LS-C133148 from LifeSpan Bioscience
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DAZ1 Antibody - NBP1-57130 from Novus Biologicals
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DAZ1 Antibody - H00001617-A01 from Novus Biologicals
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DAZ1 Polyclonal Antibody - bs-12285R from Bioss
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DAZ1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12285R-A350 from Bioss
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