| Gene Symbol |
PGAM2
|
| Entrez Gene |
5224
|
| Alt Symbol |
GSD10, PGAM-M, PGAMM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphoglycerate mutase 2 (muscle)
|
| Other Description |
BPG-dependent PGAM 2|muscle-specific phosphoglycerate mutase|phosphoglycerate mutase 2|phosphoglycerate mutase isozyme M
|
| Swissprots |
P15259
|
| Accessions |
AAA60073 AAA64238 CBX85731 CBX85913 EAL23769 EAW61128 P15259 BC001904 AAH01904 BC073741 AAH73741 CT002473 M18172 AAA60072 XM_011515426 XP_011513728 NM_000290 NP_000281
|
| Function |
Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
|
| Tissue Specificity |
In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues.
|
| Top Pathways |
Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Central carbon metabolism in cancer, Glucagon signaling pathway, Biosynthesis of amino acids
|
