Gene Symbol | PGAM2 |
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Entrez Gene | 5224 |
Alt Symbol | GSD10, PGAM-M, PGAMM |
Species | Human |
Gene Type | protein-coding |
Description | phosphoglycerate mutase 2 (muscle) |
Other Description | BPG-dependent PGAM 2|muscle-specific phosphoglycerate mutase|phosphoglycerate mutase 2|phosphoglycerate mutase isozyme M |
Swissprots | P15259 |
Accessions | AAA60073 AAA64238 CBX85731 CBX85913 EAL23769 EAW61128 P15259 BC001904 AAH01904 BC073741 AAH73741 CT002473 M18172 AAA60072 XM_011515426 XP_011513728 NM_000290 NP_000281 |
Function | Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. |
Tissue Specificity | In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues. |
Top Pathways | Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Central carbon metabolism in cancer, Glucagon signaling pathway, Biosynthesis of amino acids |
PGAM2 CRISPR/Cas9 KO Plasmid (h) - sc-410934 from Santa Cruz Biotechnology
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PGAM2 HDR Plasmid (h) - sc-410934-HDR from Santa Cruz Biotechnology
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PGAM2 Double Nickase Plasmid (h) - sc-410934-NIC from Santa Cruz Biotechnology
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PGAM2 Double Nickase Plasmid (h2) - sc-410934-NIC-2 from Santa Cruz Biotechnology
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PGAM2 CRISPR Activation Plasmid (h) - sc-410934-ACT from Santa Cruz Biotechnology
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PGAM2 CRISPR Activation Plasmid (h2) - sc-410934-ACT-2 from Santa Cruz Biotechnology
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PGAM2 Lentiviral Activation Particles (h) - sc-410934-LAC from Santa Cruz Biotechnology
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PGAM2 Lentiviral Activation Particles (h2) - sc-410934-LAC-2 from Santa Cruz Biotechnology
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PGAM2 siRNA (h) - sc-89331 from Santa Cruz Biotechnology
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PGAM2 shRNA Plasmid (h) - sc-89331-SH from Santa Cruz Biotechnology
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PGAM2 shRNA (h) Lentiviral Particles - sc-89331-V from Santa Cruz Biotechnology
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PGAM2 RNAi - H00005224-R01 from Novus Biologicals
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MISSION® esiRNA - EHU150851 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0404 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0405 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0403 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16669 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16669 from Sigma-Aldrich
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PGAM2 siRNA (Human) - CRH3490 from Cohesion Biosciences
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Human PGAM2 siRNA - orb263992 from Biorbyt
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PGAM2 shRNA Plasmid (Human) - CHH3490 from Cohesion Biosciences
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