MED25

Gene Symbol MED25
Entrez Gene 81857
Alt Symbol ACID1, ARC92, CMT2B2, P78, PTOV2, TCBAP0758
Species Human
Gene Type protein-coding
Description mediator complex subunit 25
Other Description ARC/mediator transcriptional coactivator subunit|activator interaction domain-containing protein 1|activator-recruited cofactor 92 kDa component|mediator of RNA polymerase II transcription subunit 25|mediator of RNA polymerase II transcription, subunit 25 homolog|prostate-derived protein 78 kDa
Swissprots Q9HB34 Q707U4 O95783 Q71SY5 Q8TB55 B9TX30 Q6P143 Q9H0L5 Q6QMH5 A8K095
Accessions AAD15565 EAW52544 EAW52545 EAW52546 EAW52547 EAW52548 EAW52549 EAW52550 EAW52551 Q71SY5 AF261072 AAM20739 AF283769 AAG15589 AF447873 AAQ04648 AJ617479 CAE84581 AK055844 BAG51583 AK289460 BAF82149 AK298897 BAG61008 AK307330 AL136746 CAB66680 AY533507 AAS45401 BC021543 BC024312 AAH24312 BC065297 AAH65297 BG770032 BI520216 DC410997 EU392499 ACB88861 EU392500 ACB88862 EU392501 ACB88863 EU392502 ACB88864 EU392503 ACB88865 EU392504 ACB88866 EU392505 ACB88867 EU392506 ACB88868 EU392507 ACB88869 EU392508 ACB88870 EU392509 ACB88871 EU392510 ACB88872 EU392511 ACB88873 EU392512 ACB88874 EU392513 ACB88875 EU392514 ACB88876 EU392515 ACB88877 EU392516 ACB88878 EU392517 ACB88879 EU392518 ACB88880 EU392519 EU832505 ACE87677 EU832586 ACE86988 XM_011527353 XP_011525655 NM_030973 NP_112235
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for RARA/RXRA-mediated transcription. {ECO:0000269|PubMed:14657022, ECO:0000269|PubMed:14983011, ECO:0000269|PubMed:17641689}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14657022}.
Tissue Specificity Ubiquitously expressed. Highest levels in brain, heart, kidney, peripheral leukocytes, placenta, skeletal muscle and spleen. {ECO:0000269|PubMed:14657022, ECO:0000269|PubMed:14983011}.

Med25 CRISPR/Cas9 KO Plasmid (h) - sc-405325 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 HDR Plasmid (h) - sc-405325-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 Double Nickase Plasmid (h) - sc-405325-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 Double Nickase Plasmid (h2) - sc-405325-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 CRISPR Activation Plasmid (h) - sc-405325-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 CRISPR Activation Plasmid (h2) - sc-405325-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 Lentiviral Activation Particles (h) - sc-405325-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 Lentiviral Activation Particles (h2) - sc-405325-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Med25 siRNA (h) - sc-97106 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Med25 shRNA Plasmid (h) - sc-97106-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Med25 shRNA (h) Lentiviral Particles - sc-97106-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU140091 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13174 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13174 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MED25 siRNA (Human) - CRJ3070 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MED25 (NM_030973.3) - SHH340035 from Creative biogene

Category siRNA
Species Reactivities Human

MED25 shRNA Plasmid (Human) - CHJ3070 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MED25 miRNA 3'UTR clone - MiUTR3H-11080 from Creative biogene

Species Reactivities Human
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