Gene Symbol | IPO9 |
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Entrez Gene | 55705 |
Alt Symbol | Imp9 |
Species | Human |
Gene Type | protein-coding |
Description | importin 9 |
Other Description | importin-9|ran-binding protein 9|ranBP9 |
Swissprots | B1ASV5 Q9NW01 Q96SU6 Q96P70 Q8NCG9 Q9ULM8 Q8N1Y1 Q9P0A8 Q8N3I2 |
Accessions | CDI44530 EAW91375 EAW91376 EAW91377 Q96P70 AB033018 BAA86506 AF070633 AF161391 AAF28951 AF410465 AAL01416 AK001264 BAA91588 AK027532 BAB55181 AK055940 AK074740 BAC11173 AK094276 AK124260 AL833476 AL834323 CAD38991 BC003604 AAH03604 BC156331 AAI56332 DA861528 DB232332 XM_011509730 XP_011508032 NM_018085 NP_060555 |
Function | Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), R |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Importin-9 (C-12) - sc-103567 from Santa Cruz Biotechnology
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Importin-9 (N-14) - sc-103569 from Santa Cruz Biotechnology
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Anti-Importin 9 antibody [EP1353Y] - ab52605 from Abcam
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Anti-Importin 9 antibody [EPR1352] - ab124710 from Abcam
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Anti-Importin 9 antibody - C-terminal - ab198782 from Abcam
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Anti-IPO9 / Importin 9 Antibody (aa850-950) - LS-C47289 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa86-115, Biotin) - LS-C207134 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa86-115, FITC) - LS-C207135 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa86-115, PE) - LS-C207137 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa86-115, Azide-free, HRP) - LS-C207136 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa86-115) - LS-C329688 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (C-Terminus, clone EP1353Y) - LS-C49884 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (Internal, clone EPR1352) - LS-C138569 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa79-106) - LS-C165267 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa950-1000) IHC-plus⢠- LS-B1772 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa86-115, AP) - LS-C207132 from LifeSpan Bioscience
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Anti-IPO9 / Importin 9 Antibody (aa86-115, APC) - LS-C207133 from LifeSpan Bioscience
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Importin-9 Antibody - NB100-56499 from Novus Biologicals
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Importin-9 Antibody - NB100-56489 from Novus Biologicals
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Importin-9 Antibody - NBP1-39726 from Novus Biologicals
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Importin-9 Antibody - NBP2-31588 from Novus Biologicals
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ANTI-IPO9(N-TERMINAL) antibody produced in rabbit - SAB1307184 from Sigma-Aldrich
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Anti-Importin 9 (C-terminal) antibody produced in rabbit - SAB4200154 from Sigma-Aldrich
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Anti-IPO9 antibody produced in rabbit - HPA059540 from Sigma-Aldrich
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Anti-IPO9 antibody produced in rabbit - HPA054894 from Sigma-Aldrich
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