SEPT8

Gene Symbol SEPT8
Entrez Gene 23176
Alt Symbol SEP2
Species Human
Gene Type protein-coding
Description septin 8
Other Description septin-8
Swissprots A6NKP6 A6NC65 Q92599 Q8IX36 Q9BVB3 F6W7K9 Q8IX37
Accessions EAW62315 EAW62316 EAW62317 Q92599 AF179995 AAG09407 AF440761 AAO13878 AF440762 AAO13879 AF440763 AAO13880 AI087126 AK057797 BC001329 AAH01329 BC140759 AAI40760 BC160179 AAI60179 BC171779 AAI71779 BU739074 D86957 BAA13193 DA261871 XM_005271927 XP_005271984 XM_005271928 XP_005271985 XM_005271931 XP_005271988 XM_011543288 XP_011541590 XM_011543289 XP_011541591 NM_001300798 NP_001287727 NM_001300799 NP_001287728 NM_001098811 NP_001092281 NM_001098812 NP_001092282 NM_001098813 NP_001092283 NM_015146 NP_055961
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. {ECO:0000250, ECO:0000269|PubMed:15116257, ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In platelets, found in areas surrounding alpha-granules. {ECO:0000269|PubMed:15116257}.
Tissue Specificity Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary. {ECO:0000269|PubMed:12023038, ECO:0000269|PubMed:12909369, ECO:0000269|PubMed:15116257, ECO:0000269|PubMed:15915442}.
Top Pathways Bacterial invasion of epithelial cells

Septin 8 (D-7) - sc-390105 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Septin 8 (D-7): sc-390105. Western blot analysis of Septin 8 expression in HeLa (A) and T24 (B) whole cell lysates.

Septin 8 (G-12) - sc-514436 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Septin 8 (G-12): sc-514436. Western blot analysis of Septin 8 expression in HeLa (A), T24 (B), K-562 (C) and NTERA-2 cl.D1 (D) whole cell lysates and human hippocampus (E) and human testis (F) tissue extracts.

Septin 8 (N-15) - sc-48937 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Septin 8 (N-15): sc-48937. Western blot analysis of Septin 8 expression in K-562 whole cell lysate.

Septin 8 (H-58) - sc-134891 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Septin 8 (C-14) - sc-48936 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Septin 8 (C-14): sc-48936. Western blot analysis of Septin 11 expression in non-transfected: sc-117752 (A) and human Septin 11 transfected: sc-116662 (B) 293T whole cell lysates.

Septin 8 (D-3) - sc-390071 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Septin 8 (D-3): sc-390071. Western blot analysis of Septin 8 expression in HeLa (A) and NTERA-2 cl.D1 (B) whole cell lysates and human hippocampus tissue extract (C).

Septin 8 (C-5) - sc-390074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Septin 8 (C-5): sc-390074. Western blot analysis of Septin 8 expression in rat testis (A) and mouse testis (B) tissue extracts.

Anti-Septin 8 [EPR16099] antibody - ab191404 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16099
All lanes : Anti-Septin 8 [EPR16099] antibody (ab191404) at 1/10000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat anti-rabbit IgG, (H+L), peroxidase conjugated at 1/1000 dilution

Anti-Septin 8 antibody - ab92668 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Septin 8 antibody (ab92668) at 1/500 dilutionLane 1 : Extract from HeLa cells Lane 2 : Extract from HeLa cells with blocking peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Septin 8 antibody - ab130672 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Septin 8 antibody (ab130672) at 1/100 dilution + K562 cell lysate at 35 µg

Anti-SEPT8 / Septin 8 Antibody (clone 1G3-7D1) IHC-plus™ - LS-B6217 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1G3-7D1
Anti-SEPT8 / Septin 8 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6217 concentration 3 ug/ml.

Anti-SEPT8 / Septin 8 Antibody (clone 3G1) - LS-C134047 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G1

Anti-SEPT8 / Septin 8 Antibody (Ile203) - LS-C192139 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa406-436, APC) - LS-C269011 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa406-436, AP) - LS-C269012 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa406-436, Biotin) - LS-C269014 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa406-436, FITC) - LS-C269015 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa406-436, Azide-free, HRP) - LS-C269016 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa406-436, PE) - LS-C269017 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa406-436) - LS-C330104 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT8 / Septin 8 Antibody (aa170-219) - LS-C120358 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa cells, using SEPT8 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SEPT8 / Septin 8 Antibody (aa407-436) - LS-C168971 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SEPT8 Antibody western blot of K562 cell line lysates (35 ug/lane). The SEPT8 antibody detected the SEPT8 protein (arrow).

Septin-8 Antibody - NBP2-15116 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Septin-8 Antibody [NBP2-15116] - Sample (30 ug of whole cell lysate) A: HCT116 12% SDS PAGE, antibody diluted at 1:2000.

Septin-8 Antibody - NBP1-56210 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Septin-8 Antibody [NBP1-56210] - Analysis of extracts from HeLa cells, using SEPT8 Antibody. The lane on the right is treated with the synthesized peptide.

Septin-8 Antibody (3G1) - H00023176-M08 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G1
Immunocytochemistry/Immunofluorescence: Septin-8 Antibody (3G1) [H00023176-M08] - Analysis of monoclonal antibody to SEPT8 on HeLa cell. Antibody concentration 30 ug/ml
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