SEPT8

Gene Symbol	SEPT8
Entrez Gene	23176
Alt Symbol	SEP2
Species	Human
Gene Type	protein-coding
Description	septin 8
Other Description	septin-8
Swissprots	A6NKP6 A6NC65 Q92599 Q8IX36 Q9BVB3 F6W7K9 Q8IX37
Accessions	EAW62315 EAW62316 EAW62317 Q92599 AF179995 AAG09407 AF440761 AAO13878 AF440762 AAO13879 AF440763 AAO13880 AI087126 AK057797 BC001329 AAH01329 BC140759 AAI40760 BC160179 AAI60179 BC171779 AAI71779 BU739074 D86957 BAA13193 DA261871 XM_005271927 XP_005271984 XM_005271928 XP_005271985 XM_005271931 XP_005271988 XM_011543288 XP_011541590 XM_011543289 XP_011541591 NM_001300798 NP_001287727 NM_001300799 NP_001287728 NM_001098811 NP_001092281 NM_001098812 NP_001092282 NM_001098813 NP_001092283 NM_015146 NP_055961
Function	Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. {ECO:0000250, ECO:0000269|PubMed:15116257, ECO:0000305}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In platelets, found in areas surrounding alpha-granules. {ECO:0000269|PubMed:15116257}.
Tissue Specificity	Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary. {ECO:0000269|PubMed:12023038, ECO:0000269|PubMed:12909369, ECO:0000269|PubMed:15116257, ECO:0000269|PubMed:15915442}.
Top Pathways	Bacterial invasion of epithelial cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Septin 8 full length protein - ab161559 from Abcam Category Protein Source Wheat germ Species Human

SEPT8 / Septin 8 Antibody Blocking Peptide - LS-E4509 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Septin-8 Protein - H00023176-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SEPT8-Antibody-C-term-Blocking-Peptide - BP16836b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Septin 8 Blocking Peptide - abx161242 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Monkey, Rabbit

Septin-8 (SEPT8) - H00023176-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Septin-8 (SEPT8) - H00023176-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SEPT8 fusion protein - ag19114 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SEPT8 fusion protein - Ag2357 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Septin 8 Blocking Peptide - CBP3741 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Monkey, Rabbit

Septin 8 (I203) Peptide - BS3938P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Septin 6 (SEPT6) - RPF866Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Septin-8(41525) - CSB-YP842132HU CSB-EP842132HU CSB-BP842132HU CSB-MP842132HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Septin-8 (SEPT8) (transcript variant 2) - TP313550 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Septin-8 (SEPT8) (transcript variant 4) - TP316253 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Septin-8 (SEPT8) (transcript variant 1) - TP322095 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SEPT8 Peptide, Human - M34GP14020H from Creative Peptides Category Peptide Source Synthetic. Species Human

Septin-8 (41525), Recombinant Protein - MBS1399428 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,070.00, $2,070.00, $2,535.00, $2,535.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Septin-8 (SEPT8), Recombinant Protein - MBS1073570 from MyBioSource Category Protein Prices $1,205.00, $1,205.00, $1,425.00, $1,425.00, $1,945.00, $1,945.00, $2,410.00, $2,410.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Septin-8 (SEPT8), Recombinant Protein - MBS1134514 from MyBioSource Category Protein Prices $1,220.00, $1,220.00, $1,440.00, $1,440.00, $1,975.00, $1,975.00, $2,440.00, $2,440.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Septin-8 (SEPT8), Recombinant Protein - MBS1105385 from MyBioSource Category Protein Prices $1,220.00, $1,220.00, $1,440.00, $1,440.00, $1,975.00, $1,975.00, $2,440.00, $2,440.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Septin 8 peptide - orb234616 from Biorbyt Category Peptide

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