SLC12A7

Gene Symbol	SLC12A7
Entrez Gene	10723
Alt Symbol	KCC4
Species	Human
Gene Type	protein-coding
Description	solute carrier family 12 (potassium/chloride transporter), member 7
Other Description	K-Cl cotransporter 4|electroneutral potassium-chloride cotransporter 4|potassium/chloride transporter KCC4|solute carrier family 12 (potassium/chloride transporters), member 7|solute carrier family 12 member 7
Swissprots	A6NDS8 Q9H7I3 Q9Y666 Q4G0F3 Q9H7I7 Q9UFW2 Q96I81
Accessions	CAH25944 EAX08178 EAX08179 EAX08180 EAX08181 Q9Y666 AF105365 AAD39741 AK024493 BAB15783 AK024497 BAB15787 AK026625 AK302856 BAG64042 AL117433 CAB55921 BC007760 AAH07760 BC018982 BC098390 AAH98390 BU953746 DB451347 XM_005248231 XP_005248288 XM_006725006 XP_006725069 XM_011513939 XP_011512241 XM_011513940 XP_011512242 XM_011513941 XP_011512243 XM_011546472 XP_011544774 XM_011546473 XP_011544775 XM_011546474 XP_011544776 XR_925579 XR_925580 XR_925582 XR_951676 XR_951677 XR_951678 NM_006598 NP_006589
Function	Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Detected in muscle, brain, lung, heart and kidney.
Top Pathways	Collecting duct acid secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SLC12A7 / KCC4 Antibody Blocking Peptide - LS-E1635 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC12A7 / KCC4 Antibody Blocking Peptide - LS-E26490 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC12A7-Antibody-N-term-Blocking-peptide - BP12392a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KCC4 blocking peptide - GTX88946-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

KCC4 Peptide - AC21-1327-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

KCC4 Peptide - 45-794P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

SLC12A7 fusion protein - ag8925 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SLC12A7 fusion protein - ag8715 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Potassium Chloride Cotransporters 4 (KCC4) - RPB627Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Potassium Chloride Cotransporters 4 (KCC4) - RPB627Hu01 from Cloud-clone Category Protein Source E.coli Species Human

KCC4/SLC12A7, Peptide - MBS425174 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

KCC4/SLC12A7 Recombinant Protein Antigen - NBP1-85133PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SLC12A7 fusion protein - Ag24954 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SLC12A7 Peptide, Human - M34GP14320H from Creative Peptides Category Peptide Source Synthetic. Species Human

SLC12A7 Recombinant Protein (OPCD04645) - OPCD04645 from Aviva Systems Biology Category Protein Source E.coli Species Human

SLC12A7 Immunizing peptide - orb16914 from Biorbyt Category Peptide

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