RAB10

Gene Symbol	RAB10
Entrez Gene	10890
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	RAB10, member RAS oncogene family
Other Description	GTP-binding protein RAB10|ras-related GTP-binding protein|ras-related protein Rab-10
Swissprots	Q6IA52 P61026 Q9H0T3 D6W538
Accessions	AAX93140 AAY24262 EAX00710 EAX00711 P61026 AF086917 AAP97147 AF091032 AAF00045 AF106681 AAD43034 AF297660 AAG13413 AF498945 AAM21093 AK023223 BAB14474 AK025136 AL136650 CAB66585 AL517754 BC000896 AAH00896 CR457303 CAG33584 DA295568 EU831649 ACE87249 EU831733 ACE86567 HQ447911 ADQ32395 NM_016131 NP_057215
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward
Subcellular Location	Cytoplasmic vesicle membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Endosome membrane. Recycling endosome membrane. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Cell projection, cilium. Endoplasmic reticulum membrane. Note=Associates with SLC2A4/GLUT4 storage vesicles. Localizes to the base of the cilium. Transiently associates with phagosomes (By similarity). According to PubMed:23263280 localizes to the endoplasmic reticulum at domains of new tubule growth. {ECO:0000250}.
Top Pathways	AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RAB10 full length protein - ab40648 from Abcam Category Protein Source E. coli Species Human

Human RAB10 full length protein - ab140063 from Abcam Category Protein Source E. coli Species Human

RAB10 Antibody Blocking Peptide - LS-E1465 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAB10 Antibody Blocking Peptide - LS-E10713 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAB10 Recombinant Protein - H00010890-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human RAB10 Protein - NBP2-23392 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

RAB10-Antibody-Center-Blocking-peptide - BP12172c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human RAB10 protein - orb191143 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Rab10 Blocking Peptide - 33R-3739 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAB10 protein (His tag) - 80R-2667 from Fitzgerald Category Protein Prices $270.00 Sizes 50 µg Source E.coli

RAB10 (1-200, His-tag) - AR50787PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

RAB10 (1-200, His-tag) - AR50787PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

RAB10 - H00010890-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAB10 - H00010890-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAB10, 1-200aa Human, His tag, E.coli - 01-P1963 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

RAB10 fusion protein - ag2473 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

RAB10 fusion protein - Ag18098 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Ras-related protein Rab-10 - GWB-81EE3D from Genway Biotech Category Protein Prices $230.00, $2,500.00 Sizes 50 µg, 1 mg Source E Coli Species Human

RAB10, 1-200aa Human, His tag, E.coli - GWB-PPST51 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human RAB10, T7 -tagged - RAB10-31037TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Ras-related protein Rab-10(RAB10) - CSB-YP019152HU CSB-EP019152HU CSB-BP019152HU CSB-MP019152HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RAB10, 1-200aa, Human, His tag, E.coli (Denatured) - ATGP1963 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

RAB10, Member RAS Oncogene Family Protein (Recombinant) - abx262581 from Abbexa Category Protein

RAB10 - TP301464 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RAB10 Recombinant Protein Antigen - NBP1-92307PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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