RAB10

Gene Symbol	RAB10
Entrez Gene	10890
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	RAB10, member RAS oncogene family
Other Description	GTP-binding protein RAB10|ras-related GTP-binding protein|ras-related protein Rab-10
Swissprots	Q6IA52 P61026 Q9H0T3 D6W538
Accessions	AAX93140 AAY24262 EAX00710 EAX00711 P61026 AF086917 AAP97147 AF091032 AAF00045 AF106681 AAD43034 AF297660 AAG13413 AF498945 AAM21093 AK023223 BAB14474 AK025136 AL136650 CAB66585 AL517754 BC000896 AAH00896 CR457303 CAG33584 DA295568 EU831649 ACE87249 EU831733 ACE86567 HQ447911 ADQ32395 NM_016131 NP_057215
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward
Subcellular Location	Cytoplasmic vesicle membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Endosome membrane. Recycling endosome membrane. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Cell projection, cilium. Endoplasmic reticulum membrane. Note=Associates with SLC2A4/GLUT4 storage vesicles. Localizes to the base of the cilium. Transiently associates with phagosomes (By similarity). According to PubMed:23263280 localizes to the endoplasmic reticulum at domains of new tubule growth. {ECO:0000250}.
Top Pathways	AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rab10 (D36C4) XP ® Rabbit mAb - 8127 from Cell Signaling Technology Prices $109.00, $277.00 Sizes 20 µl (2 western blots), 100 µl (10 western blots) Host Rabbit Clonality Monoclonal Clone D36C4

Rab10 Antibody - 4262 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

Rab 10 (C-18) - sc-6564 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Rab 10 (2A1C9) - sc-101429 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Rab 10 (L-12) - sc-26589 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-RAB10 antibody - ab110517 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 antibody [4E2] - ab104859 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4E2

Anti-RAB10 antibody [EPR13242] - ab181367 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR13242

Anti-RAB10 Antibody - LS-C131812 from LifeSpan Bioscience Prices $445.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (aa89-117, AP) - LS-C207549 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (aa89-117, APC) - LS-C207550 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (aa89-117, Biotin) - LS-C207551 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (aa89-117, FITC) - LS-C207552 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (aa89-117, Azide-free, HRP) - LS-C207553 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (aa89-117, PE) - LS-C207554 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (Biotin) - LS-C316789 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (C-Terminus) - LS-C134903 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (HRP) - LS-C316792 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (FITC) - LS-C316790 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody - LS-C316793 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (aa96-125) - LS-C324460 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB10 Antibody (clone 4E2) - LS-C169230 from LifeSpan Bioscience Prices $345.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4E2

Anti-RAB10 Antibody (aa89-117) - LS-C162354 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

RAB10 Antibody (4E2) - NBP1-51634 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 4E2

RAB10 Antibody - NBP1-92307 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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