IL17C

Gene Symbol	IL17C
Entrez Gene	27189
Alt Symbol	CX2, IL-17C
Species	Human
Gene Type	protein-coding
Description	interleukin 17C
Other Description	cytokine CX2\|interleukin-17C
Swissprots	Q3MIG8 Q9P0M4 Q9HC75
Accessions	CAH18037 CAL40892 CAO02250 CAS97406 CAT03419 EAW66798 Q9P0M4 AF152099 AAF28105 AY358471 AAQ88835 BC069152 AAH69152 BC069410 BC101835 AAI01836 BC112196 AAI12197 NM_013278 NP_037410
Function	Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. {ECO:0000269\|PubMed:21993848}.
Subcellular Location	Secreted.

IL-17C (A-16) - sc-11143 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

IL-17C (C-20) - sc-11145 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

IL-17C (D-15) - sc-11144 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

IL-17C (N-20) - sc-11142 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-IL17C antibody - ab153896 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IL17C antibody (ab153896) at 1/1000 dilution + A549 whole cell lysate at 30 µg

Anti-IL17C antibody - ab167284 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human pancreas tissue labeling IL17C with ab167284 at 3&microg/ml.

Anti-IL17C antibody - ab77183 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-IL17C antibody (ab77183) at 1 µg/mlLane 1 : THP1 (Human acute monocytic leukemia cell line) Whole Cell LysateLane 2 : Raji (Human Burkitt's lymphoma cell line) Whole Cell LysateLane 3 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-IL17C antibody - ab67250 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-IL17C antibody (ab67250) at 1/500 dilutionLane 1 : IL17 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg/ml per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-IL17C antibody [MM0375-9P31] - ab90941 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	MM0375-9P31

Anti-IL17C Antibody (aa36-187) - LS-C294862 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL17C Antibody (aa7-159) - LS-C294864 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL17C Antibody (APC) - LS-C37039 from LifeSpan Bioscience

Prices	$545.00
Sizes	100 tst
Host	Mouse
Clonality	Monoclonal

Anti-IL17C Antibody (CF) - LS-C37040 from LifeSpan Bioscience

Prices	$445.00
Sizes	100 tst
Host	Mouse
Clonality	Monoclonal

Anti-IL17C Antibody (PE) - LS-C37041 from LifeSpan Bioscience

Prices	$495.00
Sizes	100 tst
Host	Mouse
Clonality	Monoclonal

Anti-IL17C Antibody - LS-C308446 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-IL17C Antibody - LS-C310741 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-IL17C Antibody - LS-C310746 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-IL17C Antibody (aa19-197) - LS-C346424 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-IL17C Antibody - LS-C70965 from LifeSpan Bioscience

Prices	$495.00
Sizes	100 µg
Host	Rat
Clonality	Monoclonal

IL-17C Antibody - NBP2-27100 from Novus Biologicals

Prices	$259.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: IL17C Antibody [NBP2-27100] - Analysis of IL-17C using IL17C antibody. THP1 cell lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of IL17C antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

IL-17C Antibody [Unconjugated] - AF1234 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

IL-17C Antibody - NBP2-14990 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: IL17C Antibody [NBP2-14990] - Sample (30 ug of whole cell lysate) A: A549 12% SDS PAGE; antibody diluted at 1:1000.

IL-17C Antibody - H00027189-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

IL-17C Antibody - NBP2-39046 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

IL-17C Antibody - H00027189-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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