IL17C

Gene Symbol	IL17C
Entrez Gene	27189
Alt Symbol	CX2, IL-17C
Species	Human
Gene Type	protein-coding
Description	interleukin 17C
Other Description	cytokine CX2|interleukin-17C
Swissprots	Q3MIG8 Q9P0M4 Q9HC75
Accessions	CAH18037 CAL40892 CAO02250 CAS97406 CAT03419 EAW66798 Q9P0M4 AF152099 AAF28105 AY358471 AAQ88835 BC069152 AAH69152 BC069410 BC101835 AAI01836 BC112196 AAI12197 NM_013278 NP_037410
Function	Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. {ECO:0000269|PubMed:21993848}.
Subcellular Location	Secreted.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IL17C full length protein - ab162110 from Abcam Category Protein Source Wheat germ Species Human

Human IL17C full length protein - ab193756 from Abcam Category Protein Source Mammalian Species Human

Human IL17C full length protein - ab181967 from Abcam Category Protein Source Insect cells Species Human

IL17C peptide - ab94887 from Abcam Category Peptide

Mouse IL17C full length protein - ab181944 from Abcam Category Protein Source Insect cells Species Mouse

IL-17C Recombinant Protein - H00027189-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IL-17C Protein - NBP1-43210 from Novus Biologicals Category Protein Prices $249.00 Sizes 5 µg

IL-17C Protein - NBP1-43208 from Novus Biologicals Category Protein Prices $249.00 Sizes 5 µg

IL-17C Protein - NBP1-42912 from Novus Biologicals Category Protein Prices $829.00 Sizes 100 µg

IL-17C Protein - NBP1-42910 from Novus Biologicals Category Protein Prices $729.00 Sizes 100 µg

Recombinant Human IL-17C - 1234-IL-025 from R&D Systems Category Protein Source E. coli-derived, His19-Val197, with an N-terminal Met

Recombinant Human IL-17C, CF - 1234-IL-025/CF from R&D Systems Category Protein Source E. coli-derived, His19-Val197, with an N-terminal Met

Recombinant IL-21 (OPSD00154) - OPSD00154 from Aviva Systems Biology Category Protein Prices $105.00 Sizes 2 µg

IL17C protein - 30R-2255 from Fitzgerald Category Protein Source Insect cells Species Human

IL17C protein - 30R-2257 from Fitzgerald Category Protein Source Insect cells Species Human

IL17C protein - 30R-2176 from Fitzgerald Category Protein Source E.coli Species Human

Human Interleukin 17C Protein - abx067478 from Abbexa Category Protein Source E.coli Species Human

Interleukin-17C / IL17C - H00027189-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Interleukin-17C / IL17C - H00027189-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

IL17C fusion protein - Ag13115 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human IL17C, His-tagged - IL17C-14154H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Interleukin 17C Carrier-Free, His-tagged - IL17C-293H from Creative Biomart Category Protein Source Insect cell .

Recombinant Human Interleukin 17C, Fc Chimera - IL17C-280H from Creative Biomart Category Protein Source Mammalian cells.

Recombinant Human Interleukin 17C, His-tagged - IL17C-291H from Creative Biomart Category Protein Source Insect cell .

Recombinant Interleukin 17C (IL17C) - RPD347Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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