GCNT3

Gene Symbol GCNT3
Entrez Gene 9245
Alt Symbol C2/4GnT, C24GNT, C2GNT2, C2GNTM, GNTM
Species Human
Gene Type protein-coding
Description glucosaminyl (N-acetyl) transferase 3, mucin type
Other Description C2GnT-mucin type|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3|beta1,6-N-acetylglucosaminyltransferase-M|beta1,6GlcNAc-transferase|core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase|hC2GnT-M|mucus-type core 2 beta-1,6-N-acetylglucosaminyltransferase
Swissprots O95395
Accessions CAC17334 CAC34676 EAW77571 EAW77572 O95395 AF038650 AAD21525 AF102542 AAD10824 AK312852 BAG35705 BC017032 AAH17032 BP243086 EF152283 ABM21534 HQ448271 ADQ32751 NM_004751 NP_004742
Function Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. {ECO:0000269|PubMed:9915862}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced. {ECO:0000269|PubMed:17303715, ECO:0000269|PubMed:9915862}.
Top Pathways Mucin type O-Glycan biosynthesis

Human GCNT3 full length protein - ab160399 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160399 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human GCNT3 protein fragment - ab160400 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160400 on a 12.5% SDS-PAGE stained with Coomassie Blue.

GCNT3 Antibody Blocking Peptide - LS-E636 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GCNT3 Antibody Blocking Peptide - LS-E4518 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GCNT3 Antibody Blocking Peptide - LS-E16014 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GCNT3 Antibody Blocking Peptide - LS-E26569 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GCNT3 Antibody Blocking Peptide - LS-E26568 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GCNT3 Antibody Blocking Peptide - LS-E29618 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

GCNT3 Antibody Blocking Peptide - LS-E29619 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

GCNT3 Antibody Blocking Peptide - LS-E29813 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

GCNT3 Antibody Blocking Peptide - LS-E29812 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human GCNT3 Protein - H00009245-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human GCNT3 Protein - H00009245-P01 from Novus Biologicals

Category Protein
Prices $250.00
Sizes 2 µg
Source Wheat Germ
Species Human

GCNT3-Antibody-C-term-Blocking-peptide - BP10975b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

GCNT3-Antibody-N-term-Blocking-Peptide - BP16849a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

GCNT3 (aa 273 to 284) blocking peptide - GTX88861-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

GCNT3 (aa 410 to 422) blocking peptide - GTX88863-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Rat

GCNT3 Blocking Peptide - 33R-1261 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

GCNT3 Peptide - AC21-1404-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

GCNT3 Peptide - AC21-1405-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

GCNT3 - H00009245-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

GCNT3 - H00009245-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

GCNT3 - H00009245-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

GCNT3 - H00009245-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

GCNT3 Peptide - 46-664P from ProSci

Category Peptide
Species Human
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