Dio3

Gene Symbol	Dio3
Entrez Gene	107585
Alt Symbol	-
Species	Mouse
Gene Type	protein-coding
Description	deiodinase, iodothyronine type III
Other Description	5DIII|DIOIII|type 3 DI|type III iodothyronine deiodinase|type-III 5'-deiodinase
Swissprots	Q91ZI8 G3UY28 Q3UKD2
Accessions	AAL23960 EDL18680 Q91ZI8 AK140797 BAE24483 AK146060 BAE26869 AU017368 BC106847 AAI06848 BC106848 AAI06849 BX638763 NM_172119 NP_742117
Function	Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Deiodinase, Iodothyronine, Type III (DIO3) - RPF989Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Deiodinase, Iodothyronine, Type III (DIO3) - RPF989Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Type III iodothyronine deiodinase(Dio3) - CSB-YP856337MO CSB-EP856337MO CSB-BP856337MO CSB-MP856337MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse DIO3 Protein - DIO3-4595M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

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