Dio3

Gene Symbol Dio3
Entrez Gene 107585
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description deiodinase, iodothyronine type III
Other Description 5DIII|DIOIII|type 3 DI|type III iodothyronine deiodinase|type-III 5'-deiodinase
Swissprots Q91ZI8 G3UY28 Q3UKD2
Accessions AAL23960 EDL18680 Q91ZI8 AK140797 BAE24483 AK146060 BAE26869 AU017368 BC106847 AAI06848 BC106848 AAI06849 BX638763 NM_172119 NP_742117
Function Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

DIO3 CRISPR/Cas9 KO Plasmid (m) - sc-430733 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 HDR Plasmid (m) - sc-430733-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 Double Nickase Plasmid (m) - sc-430733-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 Double Nickase Plasmid (m2) - sc-430733-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 CRISPR Activation Plasmid (m) - sc-430733-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 CRISPR Activation Plasmid (m2) - sc-430733-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 Lentiviral Activation Particles (m) - sc-430733-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 Lentiviral Activation Particles (m2) - sc-430733-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

DIO3 siRNA (m) - sc-77151 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

DIO3 shRNA Plasmid (m) - sc-77151-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

DIO3 shRNA (m) Lentiviral Particles - sc-77151-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU008571 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN30000 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30000 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DIO3 siRNA (Mouse) - CRN0844 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

DIO3 - MBS8210144 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse DIO3 (NM_172119.2) - SHH278137 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Dio3(NM_172119.2) - SHH005663 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse DIO3 siRNA - orb290319 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

DIO3 shRNA Plasmid (Mouse) - CHN0844 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

DIO3 miRNA 3'UTR clone - MiUTR1M-03868 from Creative biogene

Species Reactivities Mouse
Search more