RECQL5

Gene Symbol	RECQL5
Entrez Gene	9400
Alt Symbol	RECQ5
Species	Human
Gene Type	protein-coding
Description	RecQ protein-like 5
Other Description	ATP-dependent DNA helicase Q5|DNA helicase, RecQ-like type 5
Swissprots	Q9UNC8 Q9P1W7 Q9H0B1 Q6P4G0 O94762
Accessions	AAD43061 AAD43062 EAW89289 EAW89290 EAW89291 EAW89292 EAW89293 EAW89294 EAW89295 O94762 AB006533 BAA74454 AB042823 BAA95952 AB042824 BAA95953 AB042825 BAA95954 AF193041 AAG22469 AI537883 AI684041 AK075084 BAG52064 AK304168 BAH14123 AL136869 CAB66803 BC000570 AAH00570 BC005103 AAH05103 BC016911 AAH16911 BC042989 BC063440 AAH63440 BI116483 BP272369 CR533497 CAG38528 DB091647 EF491799 EF560729 ABQ59039 N53539 XM_005257818 XP_005257875 XM_005257822 XP_005257879 XM_005257823 XP_005257880 XM_006722186 XP_006722249 XM_011525482 XP_011523784 XM_011525483 XP_011523785 XM_011525484 XP_011523786 XM_011525485 XP_011523787 XM_011525486 XP_011523788 NM_001003715 NP_001003715 NM_001003716 NP_001003716 NM_004259 NP_004250
Function	Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination. {ECO:0000269|PubMed:20231364, ECO:0000269|PubMed:20348101, ECO:0000269|PubMed:20643585, ECO:0000269|PubMed:22013166, ECO:0000269|PubMed:22973052, ECO:0000269|PubMed:23715498, ECO:0000269|PubMed:23748380}.
Subcellular Location	Isoform Gamma: Cytoplasm.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RECQL5 full length protein - ab132275 from Abcam Category Protein Source Wheat germ Species Human

Human RECQL5 peptide - ab31608 from Abcam Category Peptide

RECQ5 / RECQL5 Antibody Blocking Peptide - LS-E13016 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RECQ5 / RECQL5 Antibody Blocking Peptide - LS-E6641 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RECQL5 Protein - H00009400-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RECQL5-AntibodyCenter-Blocking-peptide - BP19444c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RecQL5 Blocking Peptide - 33R-1661 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RecQ5 / RECQL5 - H00009400-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RecQ5 / RECQL5 - H00009400-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RECQL5 fusion protein - Ag3145 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RECQL5, GST-tagged - RECQL5-2244H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human RECQL5, His-tagged - RECQL5-3748H from Creative Biomart Category Protein Source E. Coli or Yeast Species Human

Recombinant Human ATP-dependent DNA helicase Q5(RECQL5) ,partial - CSB-YP019539HU CSB-EP019539HU CSB-BP019539HU CSB-MP019539HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ATP-dependent DNA helicase Q5(RECQL5) ,partial, Recombinant Protein - MBS1132487 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

RECQL5 Recombinant Protein Antigen - NBP1-83438PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RECQL5 Recombinant Protein Antigen - NBP1-83437PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RECQL5 Peptide, Human - M34GP13142H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more