RECQL5

Gene Symbol RECQL5
Entrez Gene 9400
Alt Symbol RECQ5
Species Human
Gene Type protein-coding
Description RecQ protein-like 5
Other Description ATP-dependent DNA helicase Q5|DNA helicase, RecQ-like type 5
Swissprots Q9UNC8 Q9P1W7 Q9H0B1 Q6P4G0 O94762
Accessions AAD43061 AAD43062 EAW89289 EAW89290 EAW89291 EAW89292 EAW89293 EAW89294 EAW89295 O94762 AB006533 BAA74454 AB042823 BAA95952 AB042824 BAA95953 AB042825 BAA95954 AF193041 AAG22469 AI537883 AI684041 AK075084 BAG52064 AK304168 BAH14123 AL136869 CAB66803 BC000570 AAH00570 BC005103 AAH05103 BC016911 AAH16911 BC042989 BC063440 AAH63440 BI116483 BP272369 CR533497 CAG38528 DB091647 EF491799 EF560729 ABQ59039 N53539 XM_005257818 XP_005257875 XM_005257822 XP_005257879 XM_005257823 XP_005257880 XM_006722186 XP_006722249 XM_011525482 XP_011523784 XM_011525483 XP_011523785 XM_011525484 XP_011523786 XM_011525485 XP_011523787 XM_011525486 XP_011523788 NM_001003715 NP_001003715 NM_001003716 NP_001003716 NM_004259 NP_004250
Function Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination. {ECO:0000269|PubMed:20231364, ECO:0000269|PubMed:20348101, ECO:0000269|PubMed:20643585, ECO:0000269|PubMed:22013166, ECO:0000269|PubMed:22973052, ECO:0000269|PubMed:23715498, ECO:0000269|PubMed:23748380}.
Subcellular Location Isoform Gamma: Cytoplasm.
Tissue Specificity Ubiquitous.

RecQL5 CRISPR/Cas9 KO Plasmid (h) - sc-406407 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 HDR Plasmid (h) - sc-406407-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 Double Nickase Plasmid (h) - sc-406407-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 Double Nickase Plasmid (h2) - sc-406407-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 CRISPR Activation Plasmid (h) - sc-406407-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 CRISPR Activation Plasmid (h2) - sc-406407-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 Lentiviral Activation Particles (h) - sc-406407-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 Lentiviral Activation Particles (h2) - sc-406407-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RecQL5 siRNA (h) - sc-38221 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RecQL5 shRNA Plasmid (h) - sc-38221-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RecQL5 shRNA (h) Lentiviral Particles - sc-38221-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RECQL5 RNAi - H00009400-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RECQL5 RNAi - H00009400-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

RECQL5 RNAi - H00009400-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU074851 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18122 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18122 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RECQL5 siRNA (Human) - CRH6230 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RECQL5 - MBS8213971 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RECQL5 (NM_004259.6) - SHH391624 from Creative biogene

Category siRNA
Species Reactivities Human

Human RECQL5 siRNA - orb266732 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RECQL5 shRNA Plasmid (Human) - CHH6230 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RECQL5 miRNA 3'UTR clone - MiUTR3H-06269 from Creative biogene

Species Reactivities Human

RECQL5 miRNA 3'UTR clone - MiUTR3H-06270 from Creative biogene

Species Reactivities Human
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