| Gene Symbol |
AKAP12
|
| Entrez Gene |
9590
|
| Alt Symbol |
AKAP250, SSeCKS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
A kinase (PRKA) anchor protein 12
|
| Other Description |
A-kinase anchor protein 12|A-kinase anchor protein, 250kDa|AKAP 250|Src-Suppressed C Kinase Substrate|kinase scaffold protein gravin|myasthenia gravis autoantigen gravin
|
| Swissprots |
Q68D82 Q5TGN1 Q4LE68 O00310 Q99970 Q5SZ80 Q02952 O00498
|
| Accessions |
EAW47753 EAW47754 EAW47755 Q02952 AB003476 BAA19927 AB210003 BAE06085 AF001504 AAB58938 AF086250 AK024598 AK307578 AK307673 AK307739 BC000188 BC015830 BC022814 BC033829 BC046095 BC047728 AAH47728 BC070151 AAH70151 BC117679 BC117680 BC156286 AAI56287 BC157067 AAI57068 CN480611 CR749527 CAH18338 CR936604 CAI56750 DA055364 DQ584338 M96322 AAA35931 U81607 AAC51366 XM_005267233 XP_005267290 XM_005267235 XP_005267292 NM_005100 NP_005091 NM_144497 NP_653080
|
| Function |
Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
|
| Subcellular Location |
Cytoplasm, cell cortex {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000305}. Note=May be part of the cortical cytoskeleton.
|
| Tissue Specificity |
Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells.
|