Gene Symbol | AKAP12 |
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Entrez Gene | 9590 |
Alt Symbol | AKAP250, SSeCKS |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 12 |
Other Description | A-kinase anchor protein 12|A-kinase anchor protein, 250kDa|AKAP 250|Src-Suppressed C Kinase Substrate|kinase scaffold protein gravin|myasthenia gravis autoantigen gravin |
Swissprots | Q68D82 Q5TGN1 Q4LE68 O00310 Q99970 Q5SZ80 Q02952 O00498 |
Accessions | EAW47753 EAW47754 EAW47755 Q02952 AB003476 BAA19927 AB210003 BAE06085 AF001504 AAB58938 AF086250 AK024598 AK307578 AK307673 AK307739 BC000188 BC015830 BC022814 BC033829 BC046095 BC047728 AAH47728 BC070151 AAH70151 BC117679 BC117680 BC156286 AAI56287 BC157067 AAI57068 CN480611 CR749527 CAH18338 CR936604 CAI56750 DA055364 DQ584338 M96322 AAA35931 U81607 AAC51366 XM_005267233 XP_005267290 XM_005267235 XP_005267292 NM_005100 NP_005091 NM_144497 NP_653080 |
Function | Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC). |
Subcellular Location | Cytoplasm, cell cortex {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000305}. Note=May be part of the cortical cytoskeleton. |
Tissue Specificity | Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells. |
AKAP 12 CRISPR/Cas9 KO Plasmid (h) - sc-406008 from Santa Cruz Biotechnology
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AKAP 12 HDR Plasmid (h) - sc-406008-HDR from Santa Cruz Biotechnology
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AKAP 250 Double Nickase Plasmid (h) - sc-406008-NIC from Santa Cruz Biotechnology
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AKAP 12 Double Nickase Plasmid (h2) - sc-406008-NIC-2 from Santa Cruz Biotechnology
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AKAP 250 CRISPR Activation Plasmid (h) - sc-406008-ACT from Santa Cruz Biotechnology
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AKAP 12 CRISPR Activation Plasmid (h2) - sc-406008-ACT-2 from Santa Cruz Biotechnology
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AKAP 250 Lentiviral Activation Particles (h) - sc-406008-LAC from Santa Cruz Biotechnology
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AKAP 12 Lentiviral Activation Particles (h2) - sc-406008-LAC-2 from Santa Cruz Biotechnology
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AKAP 12 siRNA (h) - sc-40305 from Santa Cruz Biotechnology
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AKAP 12 shRNA Plasmid (h) - sc-40305-SH from Santa Cruz Biotechnology
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AKAP 12 shRNA (h) Lentiviral Particles - sc-40305-V from Santa Cruz Biotechnology
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AKAP12 RNAi - H00009590-R01 from Novus Biologicals
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MISSION® esiRNA - EHU092791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3004 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3004 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07577 from Sigma-Aldrich
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AKAP12 siRNA (Human) - CRH6384 from Cohesion Biosciences
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AKAP12 RNAi - H00009590-R02 from Novus Biologicals
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AKAP12 - MBS827466 from MyBioSource
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shRNA set against Human AKAP12 (NM_005100.3) - SHH234198 from Creative biogene
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shRNA set against Human AKAP12(NM_005100.3) - SHG049879 from Creative biogene
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AKAP12 shRNA Plasmid (Human) - CHH6384 from Cohesion Biosciences
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AKAP12 miRNA 3'UTR clone - MiUTR1H-00264 from Creative biogene
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