Gene Symbol | BMP8A |
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Entrez Gene | 353500 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein 8a |
Other Description | BMP-8A|bone morphogenetic protein 8A |
Swissprots | Q5T3A5 Q7Z5Y6 |
Accessions | EAX07272 EAX07273 Q7Z5Y6 AA732526 AK024413 BAB14915 AK127199 BAC86882 AY303954 AAP74559 BC093743 AAH93743 BC112044 BC131617 AAI31618 BU616301 XM_006710616 XP_006710679 XM_011541381 XP_011539683 XM_011541382 XP_011539684 XR_946640 XR_946641 XR_946642 NM_181809 NP_861525 |
Function | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT. {ECO:0000250, ECO:0000269|PubMed:22579288}. |
Subcellular Location | Secreted {ECO:0000305}. |
Top Pathways | TGF-beta signaling pathway, Hippo signaling pathway |
Anti-BMP8a antibody - ab60290 from Abcam
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Anti-BMP8a antibody - ab74870 from Abcam
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Anti-BMP8a antibody - ab134993 from Abcam
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Anti-BMP8a antibody - C-terminal - ab154373 from Abcam
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Anti-BMP8A Antibody (aa271-298, AP) - LS-C233170 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa271-298, Biotin) - LS-C233173 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa271-298, APC) - LS-C233172 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa271-298, FITC) - LS-C233174 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa271-298, PE) - LS-C233175 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa271-298) - LS-C319853 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa271-298, Azide-free, HRP) - LS-C249528 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa101-150) - LS-C201778 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa271-298) - LS-C157584 from LifeSpan Bioscience
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Anti-BMP8A Antibody (Gln299) - LS-C177354 from LifeSpan Bioscience
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Anti-BMP8A Antibody (aa26-75) IHC-plus⢠- LS-B12041 from LifeSpan Bioscience
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BMP-8 Antibody - AF1073 from Novus Biologicals
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BMP-8a Antibody - NBP1-00727 from Novus Biologicals
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BMP-8a Antibody - NBP1-31168 from Novus Biologicals
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BMP-8a Antibody - NBP1-68407 from Novus Biologicals
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BMP-8a Antibody - NBP1-51260 from Novus Biologicals
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BMP-8 Antibody [Biotin] - BAF1073 from Novus Biologicals
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Anti-BMP8A, C-Terminal antibody produced in rabbit - SAB4501530 from Sigma-Aldrich
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Anti-BMP8A antibody produced in rabbit - SAB4300762 from Sigma-Aldrich
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Anti-BMP8A (C-terminal) antibody produced in rabbit - SAB2700395 from Sigma-Aldrich
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BMP8B Antibody - middle region (ARP64754_P050) - ARP64754_P050 from Aviva Systems Biology
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