PAIP1

Gene Symbol	PAIP1
Entrez Gene	10605
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	poly(A) binding protein interacting protein 1
Other Description	PABC1-interacting protein 1|PABP-interacting protein 1|PAIP-1|poly(A)-binding protein-interacting protein 1|polyadenylate binding protein-interacting protein 1|polyadenylate-binding protein-interacting protein 1
Swissprots	Q9BS63 O60455 A6NKV8 Q9H074 Q96B61
Accessions	EAW56067 EAW56068 EAW56069 EAW56070 Q9H074 AF013758 AAC39697 AK308270 AL136920 CAB66854 BC005295 AAH05295 BC015937 AAH15937 BG430290 BG719757 DB089732 DQ786248 DQ786326 DQ891110 ABM82036 EU176558 ABW03359 XM_005248230 XP_005248287 XM_011513938 XP_011512240 NM_006451 NP_006442 NM_182789 NP_877590 NM_183323 NP_899152
Function	Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. {ECO:0000269|PubMed:11051545, ECO:0000269|PubMed:9548260}.
Subcellular Location	Cytoplasm {ECO:0000305}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAIP1 overexpression lysate - LY405243 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PAIP1 overexpression lysate - LY405357 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PAIP1 overexpression lysate - LY430621 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PAIP1 293 Cell Lysate - 403560 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PAIP1 Overexpression Lysate (Native) - NBL1-14074 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Paip1 (h): 293 Lysate - sc-112247 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Paip1 (h): 293T Lysate - sc-171347 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Paip1 (h2): 293T Lysate - sc-172162 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

PAIP1 Over-expression Lysate Product - GWB-191448 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PAIP1 Overexpression Lysate (Native) - NBP2-10060 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PAIP1 Overexpression Lysate (Native) - NBP2-04812 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human PAIP1 Knockdown Stable Cell Line - CSC-DC011257 from Creative biogene Category Cell Line Species Human

Search more