Gene Symbol | PIP4K2B |
---|---|
Entrez Gene | 8396 |
Alt Symbol | PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta, PIP5P4KB |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
Other Description | 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta|1-phosphatidylinositol-4-phosphate kinase|1-phosphatidylinositol-5-phosphate 4-kinase 2-beta|PI(5)P 4-kinase type II beta|PIP4KII-beta|PTDINS(4)P-5-kinase|diphosphoinositide kinase 2-beta|phosphatidylinositol 5-phosphate 4-kinase type II beta|phosphatidylinositol 5-phosphate 4-kinase type-2 beta|phosphatidylinositol-4-phosphate 5-kinase, type II, beta|phosphatidylinositol-5-phosphate 4-kinase type-2 beta|ptdIns(5)P-4-kinase isoform 2-beta |
Swissprots | P78356 Q8TBP2 Q5U0E8 |
Accessions | EAW60532 EAW60533 EAW60534 EAW60535 EAW60536 P78356 AI333549 AK307169 BC027459 AAH27459 BC073896 BC094858 BM991982 BT019614 AAV38420 U85245 AAB48596 XM_011525326 XP_011523628 XM_011525327 XP_011523629 XM_011525328 XP_011523630 XM_011525329 XP_011523631 XM_011525330 XP_011523632 XM_011525331 XP_011523633 XM_011546846 XP_011545148 XM_011546847 XP_011545149 XM_011546848 XP_011545150 XM_011546849 XP_011545151 XM_011546850 XP_011545152 XM_011546851 XP_011545153 NM_003559 NP_003550 NM_138687 |
Function | Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. {ECO:0000269|PubMed:9038203}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20583997}. Cytoplasm {ECO:0000269|PubMed:20583997}. Note=Associated with the plasma membrane and the endoplasmic reticulum. {ECO:0000250}. |
Tissue Specificity | Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels in placenta, lung and liver. {ECO:0000269|PubMed:9038203}. |
Top Pathways | Inositol phosphate metabolism, Regulation of actin cytoskeleton, Phosphatidylinositol signaling system |
PIP4K2B Antibody - 9694 from Cell Signaling Technology
|
||||||||
PIPK II β (A-15) - sc-11791 from Santa Cruz Biotechnology
|
||||||||
PIPK II β (C-12) - sc-11793 from Santa Cruz Biotechnology
|
||||||||
PIPK II β (N-15) - sc-11790 from Santa Cruz Biotechnology
|
||||||||
Anti-PIP5K2 beta antibody - ab168663 from Abcam
|
||||||||
Anti-PIP5K2 beta antibody - ab101670 from Abcam
|
||||||||
Anti-PIP5K2 beta antibody - ab37794 from Abcam
|
||||||||
Anti-PIP5K2 beta antibody - C-terminal - ab186518 from Abcam
|
||||||||
Anti-PIP4K2B Antibody (C-Terminus, AP) - LS-C220332 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (C-Terminus, APC) - LS-C220333 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (C-Terminus, Biotin) - LS-C220334 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (C-Terminus, FITC) - LS-C220335 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (C-Terminus, Azide-free, HRP) - LS-C220336 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (C-Terminus, PE) - LS-C220337 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (C-Terminus) - LS-C328211 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (aa274-521) - LS-C178734 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (aa347-396) - LS-C205958 from LifeSpan Bioscience
|
||||||||
Anti-PIP4K2B Antibody (aa286-317) - LS-C101119 from LifeSpan Bioscience
|
||||||||
PIP5K2B Antibody - NBP2-19837 from Novus Biologicals
|
||||||||
PIP5K2B Antibody - NBP2-13764 from Novus Biologicals
|
||||||||
PIP5K2B Antibody - H00008396-B01P from Novus Biologicals
|
||||||||
PIP5K2B Antibody - H00008396-A01 from Novus Biologicals
|
||||||||
PIP5K2B Antibody - H00008396-D01 from Novus Biologicals
|
||||||||
Anti-PIP4K2B antibody produced in rabbit - HPA047875 from Sigma-Aldrich
|
||||||||
ANTI-PIP5K2B(C-TERMINAL) antibody produced in rabbit - SAB1307131 from Sigma-Aldrich
|