Gene Symbol | PIP4K2B |
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Entrez Gene | 8396 |
Alt Symbol | PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta, PIP5P4KB |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
Other Description | 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta|1-phosphatidylinositol-4-phosphate kinase|1-phosphatidylinositol-5-phosphate 4-kinase 2-beta|PI(5)P 4-kinase type II beta|PIP4KII-beta|PTDINS(4)P-5-kinase|diphosphoinositide kinase 2-beta|phosphatidylinositol 5-phosphate 4-kinase type II beta|phosphatidylinositol 5-phosphate 4-kinase type-2 beta|phosphatidylinositol-4-phosphate 5-kinase, type II, beta|phosphatidylinositol-5-phosphate 4-kinase type-2 beta|ptdIns(5)P-4-kinase isoform 2-beta |
Swissprots | P78356 Q8TBP2 Q5U0E8 |
Accessions | EAW60532 EAW60533 EAW60534 EAW60535 EAW60536 P78356 AI333549 AK307169 BC027459 AAH27459 BC073896 BC094858 BM991982 BT019614 AAV38420 U85245 AAB48596 XM_011525326 XP_011523628 XM_011525327 XP_011523629 XM_011525328 XP_011523630 XM_011525329 XP_011523631 XM_011525330 XP_011523632 XM_011525331 XP_011523633 XM_011546846 XP_011545148 XM_011546847 XP_011545149 XM_011546848 XP_011545150 XM_011546849 XP_011545151 XM_011546850 XP_011545152 XM_011546851 XP_011545153 NM_003559 NP_003550 NM_138687 |
Function | Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. {ECO:0000269|PubMed:9038203}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000269|PubMed:20583997}. Cytoplasm {ECO:0000269|PubMed:20583997}. Note=Associated with the plasma membrane and the endoplasmic reticulum. {ECO:0000250}. |
Tissue Specificity | Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels in placenta, lung and liver. {ECO:0000269|PubMed:9038203}. |
Top Pathways | Inositol phosphate metabolism, Regulation of actin cytoskeleton, Phosphatidylinositol signaling system |
Active human PIP5K2 beta full length protein - ab82088 from Abcam
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Human PIP5K2 beta full length protein - ab140053 from Abcam
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PIP4K2B Antibody Blocking Peptide - LS-E9451 from LifeSpan Bioscience
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PIP5K2B Recombinant Protein - H00008396-P01 from Novus Biologicals
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PIP5K2B Partial Recombinant Protein - H00008396-Q01 from Novus Biologicals
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PIP5K2B Protein - NBP2-23327 from Novus Biologicals
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PIP5K2B Peptide - P3026 from Novus Biologicals
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PIP5K2B-Antibody-C-term-Blocking-Peptide - BP8042b from Abgent, a WuXi AppTec company
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PIP4K2B protein (His tag) - 80R-2646 from Fitzgerald
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PIP4K2B / PIP5K2B (1-416, His-tag) - AR50766PU-N from Acris Antibodies
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PIP4K2B / PIP5K2B (1-416, His-tag) - AR50766PU-S from Acris Antibodies
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PIP4K2B / PIP5K2B - H00008396-P01-02 from Acris Antibodies
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PIP4K2B / PIP5K2B - H00008396-Q01-10 from Acris Antibodies
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PIP4K2B / PIP5K2B - H00008396-Q01-25 from Acris Antibodies
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PIP4K2B, 1-416aa Human, His tag, E.coli - 01-P1942 from ARP American Research Products
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PIP4K2B fusion protein - Ag4099 from Proteintech Group
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PIP4K2B fusion protein - Ag14467 from Proteintech Group
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Recombinant Human GCK, His-tagged - GCK-199H from Creative Biomart
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Recombinant Human PIP4K2B - PIP4K2B-188H from Creative Biomart
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Recombinant Human PIP4K2B - PIP4K2B-30967TH from Creative Biomart
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Recombinant Human PIP4K2B, GST-tagged - PIP4K2B-119H from Creative Biomart
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Recombinant Human PIP4K2B, GST-tagged - PIP4K2B-1725H from Creative Biomart
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Recombinant Human Phosphatidylinositol 5-phosphate 4-kinase type-2 beta(PIP4K2B) - CSB-YP018023HU CSB-EP018023HU CSB-BP018023HU CSB-MP018023HU from Cusabio
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PIP4K2B, 1-416aa, Human, His tag, E.coli - ATGP1942 from ATGen
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PIP4K2B Protein - abx163664 from Abbexa
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