Gene Symbol | C19orf40 |
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Entrez Gene | 91442 |
Alt Symbol | FAAP24 |
Species | Human |
Gene Type | protein-coding |
Description | chromosome 19 open reading frame 40 |
Other Description | Fanconi anemia-associated protein of 24 kDa |
Swissprots | Q8WUJ7 Q96FX6 B3KY46 Q9BTP7 |
Accessions | Q9BTP7 AK128668 BAG54708 BC003535 AAH03535 BC010170 AAH10170 BC020247 AAH20247 BM679170 BX390218 CD690094 CN368337 DA006539 HQ447666 ADQ32151 XM_005259393 XP_005259450 NM_001300978 NP_001287907 NM_152266 NP_689479 |
Function | Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA. {ECO:0000269|PubMed:17289582}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17289582}. |
Top Pathways | Fanconi anemia pathway |
Human FAAP24 peptide - ab49605 from Abcam
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Human FAAP24 peptide - ab49606 from Abcam
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C19orf40 fusion protein - Ag23940 from Proteintech Group
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Recombinant Human Fanconi anemia-associated protein of 24 kDa(FAAP24) - CSB-YP866280HU CSB-EP866280HU CSB-BP866280HU CSB-MP866280HU from Cusabio
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C19orf40 Protein - abx163261 from Abbexa
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FAAP24 - TP305872 from Acris Antibodies
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FAAP24 Recombinant Protein Antigen - NBP1-91876PEP from Novus Biologicals
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FAAP24-Blocking-Peptide-N-Term - BP21766a from Abgent, a WuXi AppTec company
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C19ORF40 Peptide, Human - M34GP01829H from Creative Peptides
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Fanconi anemia-associated protein of 24 kDa (FAAP24), Recombinant Protein - MBS1429677 from MyBioSource
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Recombinant Human FAAP24 Protein, MYC/DDK-tagged - FAAP24-952H from Creative Biomart
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