SEPT4

Gene Symbol	SEPT4
Entrez Gene	5414
Alt Symbol	ARTS, BRADEION, CE5B3, H5, MART, PNUTL2, SEP4, hCDCREL-2, hucep-7
Species	Human
Gene Type	protein-coding
Description	septin 4
Other Description	CE5B3 beta|apoptosis-related protein in the TGF-beta signaling pathway|bradeion beta|brain protein H5|cell division control-related protein 2|cerebral protein 7|peanut-like protein 2|septin-4|septin-M
Swissprots	O43236 B4DXV5 B3KSX9 Q9UM58 Q6IAP3 B2RD42 B4DXC6 Q9H315
Accessions	CCQ43816 EAW94440 EAW94441 EAW94442 EAW94443 EAW94444 EAW94445 EAW94446 EAW94447 EAW94448 EAW94449 EAW94450 EAW94451 EAW94452 EAW94453 O43236 AB002110 BAB70694 AB008753 BAB70695 AB010642 AF035811 AAB88512 AF073312 AAC25673 AF176379 AAG45673 AK091065 BAG52275 AK094579 BAG52891 AK126631 AK294094 BAG57432 AK295527 BAG58440 AK301914 BAG63338 AK302146 BAG63517 AK308957 AK314528 BAG37122 AK315045 AK315396 BAG37789 BC018055 BC018056 AAH18056 BC128255 BC128515 BC142968 CR457111 CAG33392 D89278 BAB46922 DA076433 DA180095 DA343015 DC361494 DQ892336 ABM83262 DQ895541 ABM86467 U88829 AAD00653 U88870 AAD00657 XM_006721949 XP_006722012 XM_006721950 XP_006722013 XM_006721951 XP_006722014 XM_006721952 XP_006722015 XM_006721954 XP_006722017 XM_006721955 XP_006722018 XM_011524910 XP_011523212 XM_011524911 XP_011523213 XM_011524912 XP_011523214 NM_001198713 NP_001185642 NM_001256782 NP_001243711 NM_001256822 NP_001243751 NM_004574 NP_004565 NM_080415 NP_536340 NM_080416 NP_536341 NR_037155 NR_104196 NR_104197 NM_080417
Function	Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli. {ECO:0000250, ECO:0000269|PubMed:11146656, ECO:0000269|PubMed:15029247, ECO:0000269|PubMed:15116257, ECO:0000269|PubMed:15837787, ECO:0000269|PubMed:9889007, ECO:0000305}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In platelets, found in areas surrounding alpha-granules. {ECO:0000269|PubMed:11146656, ECO:0000269|PubMed:15029247, ECO:0000269|PubMed:15116257}.
Tissue Specificity	Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in platelets. {ECO:0000269|PubMed:11146656, ECO:0000269|PubMed:11167005, ECO:0000269|PubMed:11511094, ECO:0000269|PubMed:15116257, ECO:0000269|PubMed:15915442, ECO:0000269|PubMed:9889007}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ARTS full length protein - ab131801 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ARTS peptide - ab9652 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

SEPT4 / Septin 4 Antibody Blocking Peptide - LS-E27503 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SEPT4 / Septin 4 Antibody Blocking Peptide - LS-E27502 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SEPT4 / Septin 4 Antibody Blocking Peptide - LS-E29993 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Septin-4 Protein - H00005414-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SEPT4 Immunizing peptide - orb59913 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

SEPT4 Peptide - AC21-2325-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SEPT4 Peptide - AC21-2326-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Septin-4 (SEPT4) - H00005414-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Septin-4 (SEPT4) - H00005414-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ARTS Control Peptide - AP30082CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ARTS Peptide - 3025P from ProSci Category Peptide Species Human

SEPT4 Peptide - 42-672P from ProSci Category Peptide Species Human, Mouse

SEPT4 Peptide - 42-673P from ProSci Category Peptide Species Human, Mouse

SEPT4 fusion protein - ag3185 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Septin-4(SEPT4) - CSB-YP021027HU CSB-EP021027HU CSB-BP021027HU CSB-MP021027HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Septin-4 (SEPT4) (transcript variant 1) - TP313106 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Septin-4 (SEPT4) (transcript variant 2) - TP315054 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SEPT4, Peptide - MBS427565 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

SEPT4, Peptide - MBS428155 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Dog, Bovine

Synthetic Human SEPT4 (aa 3-14) Blocking Peptide - PX226BP from Cell Science Category Peptide Prices $170.00 Sizes 50 μg Species Human

Septin-4 Recombinant Protein Antigen - NBP1-90094PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Septin-4 Recombinant Protein Antigen - NBP1-90093PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Septin-2 Recombinant Protein Antigen - NBP1-85212PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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