SEPT4

Gene Symbol SEPT4
Entrez Gene 5414
Alt Symbol ARTS, BRADEION, CE5B3, H5, MART, PNUTL2, SEP4, hCDCREL-2, hucep-7
Species Human
Gene Type protein-coding
Description septin 4
Other Description CE5B3 beta|apoptosis-related protein in the TGF-beta signaling pathway|bradeion beta|brain protein H5|cell division control-related protein 2|cerebral protein 7|peanut-like protein 2|septin-4|septin-M
Swissprots O43236 B4DXV5 B3KSX9 Q9UM58 Q6IAP3 B2RD42 B4DXC6 Q9H315
Accessions CCQ43816 EAW94440 EAW94441 EAW94442 EAW94443 EAW94444 EAW94445 EAW94446 EAW94447 EAW94448 EAW94449 EAW94450 EAW94451 EAW94452 EAW94453 O43236 AB002110 BAB70694 AB008753 BAB70695 AB010642 AF035811 AAB88512 AF073312 AAC25673 AF176379 AAG45673 AK091065 BAG52275 AK094579 BAG52891 AK126631 AK294094 BAG57432 AK295527 BAG58440 AK301914 BAG63338 AK302146 BAG63517 AK308957 AK314528 BAG37122 AK315045 AK315396 BAG37789 BC018055 BC018056 AAH18056 BC128255 BC128515 BC142968 CR457111 CAG33392 D89278 BAB46922 DA076433 DA180095 DA343015 DC361494 DQ892336 ABM83262 DQ895541 ABM86467 U88829 AAD00653 U88870 AAD00657 XM_006721949 XP_006722012 XM_006721950 XP_006722013 XM_006721951 XP_006722014 XM_006721952 XP_006722015 XM_006721954 XP_006722017 XM_006721955 XP_006722018 XM_011524910 XP_011523212 XM_011524911 XP_011523213 XM_011524912 XP_011523214 NM_001198713 NP_001185642 NM_001256782 NP_001243711 NM_001256822 NP_001243751 NM_004574 NP_004565 NM_080415 NP_536340 NM_080416 NP_536341 NR_037155 NR_104196 NR_104197 NM_080417
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli. {ECO:0000250, ECO:0000269|PubMed:11146656, ECO:0000269|PubMed:15029247, ECO:0000269|PubMed:15116257, ECO:0000269|PubMed:15837787, ECO:0000269|PubMed:9889007, ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In platelets, found in areas surrounding alpha-granules. {ECO:0000269|PubMed:11146656, ECO:0000269|PubMed:15029247, ECO:0000269|PubMed:15116257}.
Tissue Specificity Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in platelets. {ECO:0000269|PubMed:11146656, ECO:0000269|PubMed:11167005, ECO:0000269|PubMed:11511094, ECO:0000269|PubMed:15116257, ECO:0000269|PubMed:15915442, ECO:0000269|PubMed:9889007}.

Septin 4 CRISPR/Cas9 KO Plasmid (h) - sc-402288 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 HDR Plasmid (h) - sc-402288-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 Double Nickase Plasmid (h) - sc-402288-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 Double Nickase Plasmid (h2) - sc-402288-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 CRISPR Activation Plasmid (h) - sc-402288-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 CRISPR Activation Plasmid (h2) - sc-402288-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 Lentiviral Activation Particles (h) - sc-402288-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 Lentiviral Activation Particles (h2) - sc-402288-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Septin 4 siRNA (h) - sc-36476 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Septin 4 shRNA Plasmid (h) - sc-36476-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Septin 4 shRNA (h) Lentiviral Particles - sc-36476-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Septin-4 RNAi - H00005414-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Septin-4 RNAi - H00005414-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Septin-4 RNAi - H00005414-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Septin-4 RNAi - H00005414-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU079321 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19105 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01259 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01259

SEPT4 siRNA (Human) - CRH3623 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SEPT4 - MBS8235789 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SEPT4 (NM_004574.3) - SHH404640 from Creative biogene

Category siRNA
Species Reactivities Human

SEPT4 shRNA Plasmid (Human) - CHH3623 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SEPT4 miRNA 3'UTR clone - MiUTR3H-06184 from Creative biogene

Species Reactivities Human

SEPT4 miRNA 3'UTR clone - MiUTR3H-06185 from Creative biogene

Species Reactivities Human
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