| Gene Symbol |
TNFSF9
|
| Entrez Gene |
8744
|
| Alt Symbol |
4-1BB-L, CD137L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tumor necrosis factor (ligand) superfamily, member 9
|
| Other Description |
4-1BB ligand|4-1BBL|homolog of mouse 4-1BB-L|receptor 4-1BB ligand|tumor necrosis factor ligand superfamily member 9
|
| Swissprots |
P41273 Q2M3S2
|
| Accessions |
EAW69076 EAW69077 P41273 AI357267 AK313999 BAG36711 BC104805 AAI04806 BC104807 AAI04808 BM790119 BX107825 U03398 AAA53134 XM_006722931 XP_006722994 NM_003811 NP_003802
|
| Function |
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. {ECO:0000269|PubMed:20032458}.
|
| Subcellular Location |
Membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
Expressed in brain, placenta, lung, skeletal muscle and kidney.
|
| Top Pathways |
Cytokine-cytokine receptor interaction
|