HMBS

Gene Symbol	HMBS
Entrez Gene	3145
Alt Symbol	PBG-D, PBGD, PORC, UPS
Species	Human
Gene Type	protein-coding
Description	hydroxymethylbilane synthase
Other Description	porphobilinogen deaminase|porphyria, acute; Chester type|pre-uroporphyrinogen synthase|uroporphyrinogen I synthase|uroporphyrinogen I synthetase
Swissprots	G3V1P4 Q16012 P08396 A8K2L0 G5EA58 P08397
Accessions	AAA60028 AAA60029 AAA60030 AAC60602 ABI36594 AHW82961 BAA01463 BAA02216 BAD36778 BAG71787 CAA48156 EAW67447 EAW67448 EAW67449 EAW67450 P08397 AK000628 AK131072 AK290275 BAF82964 AK309544 AK310343 AW139390 BC000520 AAH00520 BC008149 AAH08149 BC019323 AAH19323 BF210364 BQ020524 BX647328 CB128006 D28419 BAA05785 HQ448217 ADQ32697 HQ731552 ADX60069 M60888 X04217 CAA27801 X04808 CAA28499 XM_005271531 XP_005271588 XM_005271532 XP_005271589 XM_005271533 XP_005271590 XM_011542796 XP_011541098 NM_000190 NP_000181 NM_001024382 NP_001019553 NM_001258208 NP_001245137 NM_001258209 NP_001245138
Function	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Subcellular Location	Cytoplasm {ECO:0000305}.
Tissue Specificity	Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells. {ECO:0000269|PubMed:3422427}.
Top Pathways	Porphyrin and chlorophyll metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HMBS / PBGD ELISA Kit (Sandwich ELISA) - LS-F8287 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.27 ng/ml Range 0.781-50 ng/ml

Human HMBS ELISA Kit - abx151823 from Abbexa Category ELISA Kit Sensitivity 0.27 ng/ml Range 0.781 ng/ml - 50 ng/ml

Hydroxymethylbilane Synthase (HMBS), Human, ELISA Kit - SEE673Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.27ng/mL Range 0.78-50ng/mL

HMBS (Human) Matched Antibody Pair - H00003145-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

HMBS (Human) Matched Antibody Pair - H00003145-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Hydroxymethylbilane Synthase, ELISA Kit - MBS069417 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hydroxymethylbilane Synthase, ELISA Kit - MBS073809 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hydroxymethylbilane Synthase, ELISA Kit - MBS076652 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hydroxymethylbilane Synthase, ELISA Kit - MBS069496 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hydroxymethylbilane Synthase, ELISA Kit - MBS095674 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hydroxymethylbilane Synthase, ELISA Kit - MBS057025 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hydroxymethylbilane Synthase, ELISA Kit - MBS094710 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hydroxymethylbilane Synthase (HMBS), ELISA Kit - MBS2022994 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human HMBS is typically less than 0.27ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.78-50ng/mL

ELISA Kit for Hydroxymethylbilane Synthase (HMBS) - SEE673Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Hydroxymethylbilane Synthase (HMBS) - SEE673Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human Hydroxymethylbilane Synthase (HMBS) ELISA Kit - EKU04855 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.26 ng/mL Range 0.78-50 ng/mL

Hydroxymethylbilane Synthase (HMBS), Human, ELISA Kit - DL-HMBS-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.78-50 ng/mL

Human Porphobilinogen deaminase ELISA Kit - EKE55006 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Range 0.625-40 ng/ml

HMBS ELISA Kit (Human) (OKEH02521) - OKEH02521 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 0.12 ng/mL Range 0.625 - 40 ng/mL

Human HMBS ELISA Kit - E019142 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human HMBS is typically less than 0.27ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by addin

Human Porphobilinogen deaminase ELISA Kit - EK3686 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Range 0.625-40 ng/ml

Hydroxymethylbilane Synthase (HMBS), ELISA Kit - MBS453169 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.27ng/mL Range 0.781-50ng/mL

Porphobilinogen deaminase, ELISA Kit - MBS9427520 from MyBioSource Category ELISA Kit Prices $670.00 Sizes 96 tests Range 0.625-40 ng/mL

Hydroxymethylbilane Synthase (HMBS), ELISA Kit - MBS9371477 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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