HMBS

Gene Symbol	HMBS
Entrez Gene	3145
Alt Symbol	PBG-D, PBGD, PORC, UPS
Species	Human
Gene Type	protein-coding
Description	hydroxymethylbilane synthase
Other Description	porphobilinogen deaminase|porphyria, acute; Chester type|pre-uroporphyrinogen synthase|uroporphyrinogen I synthase|uroporphyrinogen I synthetase
Swissprots	G3V1P4 Q16012 P08396 A8K2L0 G5EA58 P08397
Accessions	AAA60028 AAA60029 AAA60030 AAC60602 ABI36594 AHW82961 BAA01463 BAA02216 BAD36778 BAG71787 CAA48156 EAW67447 EAW67448 EAW67449 EAW67450 P08397 AK000628 AK131072 AK290275 BAF82964 AK309544 AK310343 AW139390 BC000520 AAH00520 BC008149 AAH08149 BC019323 AAH19323 BF210364 BQ020524 BX647328 CB128006 D28419 BAA05785 HQ448217 ADQ32697 HQ731552 ADX60069 M60888 X04217 CAA27801 X04808 CAA28499 XM_005271531 XP_005271588 XM_005271532 XP_005271589 XM_005271533 XP_005271590 XM_011542796 XP_011541098 NM_000190 NP_000181 NM_001024382 NP_001019553 NM_001258208 NP_001245137 NM_001258209 NP_001245138
Function	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Subcellular Location	Cytoplasm {ECO:0000305}.
Tissue Specificity	Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells. {ECO:0000269|PubMed:3422427}.
Top Pathways	Porphyrin and chlorophyll metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HMBS full length protein - ab114899 from Abcam Category Protein Source Wheat germ Species Human

Human HMBS full length protein - ab123176 from Abcam Category Protein Source E. coli Species Human

HMBS / PBGD Antibody Blocking Peptide - LS-E19602 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMBS / PBGD Antibody Blocking Peptide - LS-E19601 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HMBS Recombinant Protein - H00003145-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human HMBS Protein - NBP1-99086 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

HMBS-Antibody-Center-Blocking-peptide - BP12917c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HMBS-Antibody-C-term-Blocking-Peptide - BP6904b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HMBS protein - orb168502 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

HMBS Blocking Peptide - 33R-8825 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HMBS Blocking Peptide - 33R-6388 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HMBS protein (His tag) - 80R-2177 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

HMBS (1-361, His-tag) - AR50258PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

HMBS (1-361, His-tag) - AR50258PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

HMBS - H00003145-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HMBS - H00003145-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HMBS, 1-361aa, Human, His tag, E.coli - 01-P1433 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

HMBS fusion protein - Ag6594 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HMBS fusion protein - Ag6509 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

HMBS Human - ENPS-588 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Hydroxymethylbilane Synthase Enzyme - BP002776-ENZ-581 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human Hydroxymethylbilane Synthase, His-tagged - HMBS-1929H from Creative Biomart Category Protein

Recombinant Human HMBS - HMBS-29326TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human HMBS, GST-tagged - HMBS-13835H from Creative Biomart Category Protein Source E.coli Species Human

HMBS 1-361aa - CMB-1266 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

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