Gene Symbol | TM7SF2 |
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Entrez Gene | 7108 |
Alt Symbol | ANG1, DHCR14A, NET47 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane 7 superfamily member 2 |
Other Description | C-14 sterol reductase|another new gene 1 protein|delta(14)-sterol reductase|delta-14-SR|putative sterol reductase SR-1|sterol C14-reductase |
Swissprots | O76062 A8K4H0 Q96E64 Q8IY06 Q96GZ1 O95982 |
Accessions | AAC21457 AAD09769 EAW74348 EAW74349 EAW74350 EAW74351 O76062 AF023676 AAC21450 AF096304 AAD09765 AK290935 BAF83624 AK296441 BAG59094 BC009052 AAH09052 BC012857 AAH12857 BC038353 AAH38353 BG771219 NM_001277233 NP_001264162 NM_003273 NP_003264 NR_102367 |
Function | Involved in the conversion of lanosterol to cholesterol. {ECO:0000269|PubMed:11784322}. |
Subcellular Location | Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:9878250}; Multi-pass membrane protein {ECO:0000269|PubMed:9878250}. |
Tissue Specificity | Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. {ECO:0000269|PubMed:9878250}. |
Top Pathways | Steroid biosynthesis |
TM7SF2 Antibody Blocking Peptide - LS-E16613 from LifeSpan Bioscience
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TM7SF2 Blocking Peptide - 33R-4757 from Fitzgerald
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TM7SF2 fusion protein - ag6555 from Proteintech Group
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TM7SF2 fusion protein - ag2637 from Proteintech Group
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TM7SF2 Protein - NBP1-89089PEP from Novus Biologicals
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TM7SF2 Peptide, Human - M34GP16024H from Creative Peptides
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TM7SF2 Recombinant Protein Antigen - NBP2-57265PEP from Novus Biologicals
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Delta (14)-sterol reductase (TM7SF2), Recombinant Protein - MBS1212904 from MyBioSource
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Delta(14)-sterol reductase (TM7SF2), Recombinant Protein - MBS7031347 from MyBioSource
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