Gene Symbol | TM7SF2 |
---|---|
Entrez Gene | 7108 |
Alt Symbol | ANG1, DHCR14A, NET47 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane 7 superfamily member 2 |
Other Description | C-14 sterol reductase|another new gene 1 protein|delta(14)-sterol reductase|delta-14-SR|putative sterol reductase SR-1|sterol C14-reductase |
Swissprots | O76062 A8K4H0 Q96E64 Q8IY06 Q96GZ1 O95982 |
Accessions | AAC21457 AAD09769 EAW74348 EAW74349 EAW74350 EAW74351 O76062 AF023676 AAC21450 AF096304 AAD09765 AK290935 BAF83624 AK296441 BAG59094 BC009052 AAH09052 BC012857 AAH12857 BC038353 AAH38353 BG771219 NM_001277233 NP_001264162 NM_003273 NP_003264 NR_102367 |
Function | Involved in the conversion of lanosterol to cholesterol. {ECO:0000269|PubMed:11784322}. |
Subcellular Location | Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:9878250}; Multi-pass membrane protein {ECO:0000269|PubMed:9878250}. |
Tissue Specificity | Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. {ECO:0000269|PubMed:9878250}. |
Top Pathways | Steroid biosynthesis |
TM7SF2 (E-16) - sc-162325 from Santa Cruz Biotechnology
|
||||||||
TM7SF2 (G-11) - sc-162326 from Santa Cruz Biotechnology
|
||||||||
TM7SF2 (L-12) - sc-162327 from Santa Cruz Biotechnology
|
||||||||
Anti-TM7SF2 antibody - ab104720 from Abcam
|
||||||||
Anti-TM7SF2 Antibody (aa35-84) - LS-C116303 from LifeSpan Bioscience
|
||||||||
TM7SF2 Antibody - NBP1-80548 from Novus Biologicals
|
||||||||
TM7SF2 Antibody - NBP1-89089 from Novus Biologicals
|
||||||||
TM7SF2 Polyclonal Antibody - bs-4221R from Bioss
|
||||||||
Anti-TM7SF2, (N-terminal) antibody produced in rabbit - SAB2105636 from Sigma-Aldrich
|
||||||||
Anti-TM7SF2 antibody produced in rabbit - HPA030691 from Sigma-Aldrich
|
||||||||
TM7SF2 antibody - N-terminal region (ARP45456_P050) - ARP45456_P050 from Aviva Systems Biology
|
||||||||
TM7SF2 antibody - 70R-20852 from Fitzgerald
|
||||||||
TM7SF2 antibody - 70R-6436 from Fitzgerald
|
||||||||
TM7SF2 Polyclonal Antibody - A4159 from ABclonal
|
||||||||
TM7SF2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-4221R-A350 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-4221R-A488 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-4221R-A555 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-4221R-A647 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, Cy3 Conjugated - bs-4221R-Cy3 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, Cy5 Conjugated - bs-4221R-Cy5 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, Cy5.5 Conjugated - bs-4221R-Cy5.5 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, Cy7 Conjugated - bs-4221R-Cy7 from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, FITC Conjugated - bs-4221R-FITC from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, Biotin Conjugated - bs-4221R-Biotin from Bioss
|
||||||||
TM7SF2 Polyclonal Antibody, HRP Conjugated - bs-4221R-HRP from Bioss
|