DET1

Gene Symbol DET1
Entrez Gene 55070
Alt Symbol -
Species Human
Gene Type protein-coding
Description de-etiolated homolog 1 (Arabidopsis)
Other Description DET1 homolog|de-etiolated 1|de-etiolated-1 homolog
Swissprots Q9NWD5 B3KNN6 Q2VPC0 Q7L5Y6
Accessions CAD34982 CAE88994 EAX02003 EAX02004 EAX02005 EAX02006 Q7L5Y6 AB073887 AK000965 BAA91447 AK054603 BAG51398 BC001242 AAH01242 BC064591 BC073867 BC109060 AAI09061 BC109061 AAI09062 DA655836 XM_011521747 XP_011520049 XM_011521748 XP_011520050 XM_011521749 XP_011520051 XM_011521750 XP_011520052 XM_011521751 XP_011520053 NM_001144074 NP_001137546 NM_017996 NP_060466 NR_026645
Function Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation. {ECO:0000269|PubMed:14739464}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Highly expressed in the ovary, some lymphoid organs and resting leukocytes. {ECO:0000269|PubMed:14739464}.
Top Pathways Ubiquitin mediated proteolysis

Human DET1 protein fragment - ab162952 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162952 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human DET1 Protein - H00055070-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

DET1 Peptide - P2450 from Novus Biologicals

Category Peptide
Species Human

DET1-ANtibody-C-term-Blocking-Peptide - BP7271b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

DET1 - H00055070-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

DET1 - H00055070-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

DET1 fusion protein - ag17501 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

DET1 fusion protein - ag16127 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human DET1 homolog(DET1) - CSB-YP762572HU CSB-EP762572HU CSB-BP762572HU CSB-MP762572HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

DET1 Protein - NBP2-13914PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

Det1-Blocking-Peptide-N-term - BP7271a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

DET1 Peptide, Human - M34GP04236H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

DET1 homolog (DET1), Recombinant Protein - MBS1410513 from MyBioSource

Category Protein
Prices $1,345.00, $1,345.00, $1,565.00, $1,565.00, $2,230.00, $2,230.00, $2,695.00, $2,695.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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